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Proteomic analysis of the Mycobacterium avium-containing phagosome membrane
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Medical Biochemistry
2015
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| _version_ | 1867613216351191041 |
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| access_status_str | Open Access |
| author | Pietersen, Ray-Dean Donovan |
| author2 | Thilo, Lutz |
| author_browse | Pietersen, Ray-Dean Donovan Thilo, Lutz |
| author_facet | Thilo, Lutz Pietersen, Ray-Dean Donovan |
| author_sort | Pietersen, Ray-Dean Donovan |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12226 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:37.404Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Medical Biochemistry |
| publisherStr | Division of Medical Biochemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12226 Proteomic analysis of the Mycobacterium avium-containing phagosome membrane Pietersen, Ray-Dean Donovan Thilo, Lutz Medicine Includes abstract. Includes bibliographical references (leaves 139-158). Pathogenic mycobacteria, like [Mycobacterium tuberculosis] M.tb and Mycobacterium avium (M.av), reside intracellularly in phagosomes where they are able to survive, because they block the process of phagosome maturation. ... An approach of characterizing M.av-containing phagosomes in terms of cell surface-derived glycoconjugates, revealed that these phagosomes show a 3- to 4-fold depletion of these glycoconjugates as compared to early endosomes with which the phagosomes continuously fuse and exchange membrane molecules... The aim of this study is to identify the depleted / possibly enriched cell surface derived glycoproteins on the phagosome membrane of M.av-containing phagosomes, because they might play a role in mycobacteria's intracellular survival. 2015-01-15T11:30:09Z 2015-01-15T11:30:09Z 2010 Master Thesis Masters MSc http://hdl.handle.net/11427/12226 eng application/pdf Division of Medical Biochemistry Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Pietersen, Ray-Dean Donovan Proteomic analysis of the Mycobacterium avium-containing phagosome membrane |
| thesis_degree_str | Master's |
| title | Proteomic analysis of the Mycobacterium avium-containing phagosome membrane |
| title_full | Proteomic analysis of the Mycobacterium avium-containing phagosome membrane |
| title_fullStr | Proteomic analysis of the Mycobacterium avium-containing phagosome membrane |
| title_full_unstemmed | Proteomic analysis of the Mycobacterium avium-containing phagosome membrane |
| title_short | Proteomic analysis of the Mycobacterium avium-containing phagosome membrane |
| title_sort | proteomic analysis of the mycobacterium avium containing phagosome membrane |
| topic | Medicine |
| url | http://hdl.handle.net/11427/12226 |
| work_keys_str_mv | AT pietersenraydeandonovan proteomicanalysisofthemycobacteriumaviumcontainingphagosomemembrane |