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Includes abstract.
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| Format: | Thesis |
| Language: | English |
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Division of Medical Biochemistry
2015
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| _version_ | 1867613153043415040 |
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| access_status_str | Open Access |
| author | Esau, Luke Emmanuel |
| author2 | Hendricks, Denver |
| author_browse | Esau, Luke Emmanuel Hendricks, Denver |
| author_facet | Hendricks, Denver Esau, Luke Emmanuel |
| author_sort | Esau, Luke Emmanuel |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12279 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:35.974Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Medical Biochemistry |
| publisherStr | Division of Medical Biochemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12279 Proliferative and survival pathways in oesophageal cancer Esau, Luke Emmanuel Hendricks, Denver Medical Biochemistry Includes abstract. Includes bibliographical references. Oesophageal squamous cell carcinoma (OSCC) is the 8th most common cancer worldwide with high incidence in areas that include China, Iran and South Africa. The current treatment available for OSCC does not significantly enhance patient survival. A better understanding of proliferative and survival pathways activated in OSCC could allow identification of more specific therapeutic targets, potentially improving management of OSCC. Cell surface receptors are known to play important roles in relaying signals from the extracellular environment...The aim of this study was to determine the role of EGFR, IGF-1R and CXCR2 in proliferation and survival of OSCC cells. 2015-01-20T18:11:22Z 2015-01-20T18:11:22Z 2011 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/12279 eng application/pdf Division of Medical Biochemistry Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medical Biochemistry Esau, Luke Emmanuel Proliferative and survival pathways in oesophageal cancer |
| thesis_degree_str | Doctoral |
| title | Proliferative and survival pathways in oesophageal cancer |
| title_full | Proliferative and survival pathways in oesophageal cancer |
| title_fullStr | Proliferative and survival pathways in oesophageal cancer |
| title_full_unstemmed | Proliferative and survival pathways in oesophageal cancer |
| title_short | Proliferative and survival pathways in oesophageal cancer |
| title_sort | proliferative and survival pathways in oesophageal cancer |
| topic | Medical Biochemistry |
| url | http://hdl.handle.net/11427/12279 |
| work_keys_str_mv | AT esaulukeemmanuel proliferativeandsurvivalpathwaysinoesophagealcancer |