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A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine
Includes abstract.~Includes bibliographical references (leaves 119-147).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
MRC/UCT RU for Exercise and Sport Medicine
2015
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| _version_ | 1867613499666989056 |
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| access_status_str | Open Access |
| author | Hsin-Wen Hsieh, Jennifer |
| author2 | Russell, Vivienne A |
| author_browse | Hsin-Wen Hsieh, Jennifer Russell, Vivienne A |
| author_facet | Russell, Vivienne A Hsin-Wen Hsieh, Jennifer |
| author_sort | Hsin-Wen Hsieh, Jennifer |
| collection | Thesis |
| description | Includes abstract.~Includes bibliographical references (leaves 119-147). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12368 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:37:07.605Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | MRC/UCT RU for Exercise and Sport Medicine |
| publisherStr | MRC/UCT RU for Exercise and Sport Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12368 A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine Hsin-Wen Hsieh, Jennifer Russell, Vivienne A Medicine Includes abstract.~Includes bibliographical references (leaves 119-147). Attention-Deficit/Hyperactivity Disorder (ADHD) is a childhood disorder that is behaviorally characterized by developmentally inappropriate levels of inattention, impulsivity and hyperactivity. Among several hypotheses of ADHD etiology the prevailing hypothesis implicates a hypodopaminergic system due largely to the successes of the use of psychostimulants such as methylphenidate, that increase extracellular levels of dopamine (DA) and/or norepinephrine (NE) for the treatment of symptoms. In this study, the spontaneously hypertensive rat (SHR), the most widely accepted model for ADHD, is compared with the Wistar-Kyoto (WKY) and Sprague-Dawley (SD) rat strains as controls 2015-02-04T19:08:01Z 2015-02-04T19:08:01Z 2010 Master Thesis Masters MSc http://hdl.handle.net/11427/12368 eng application/pdf MRC/UCT RU for Exercise and Sport Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medicine Hsin-Wen Hsieh, Jennifer A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine |
| thesis_degree_str | Master's |
| title | A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine |
| title_full | A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine |
| title_fullStr | A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine |
| title_full_unstemmed | A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine |
| title_short | A study of an animal model of Attention-Deficit/ Hyperactivity Disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine |
| title_sort | study of an animal model of attention deficit hyperactivity disorder using in vivo chronoamperometry and behavioural responses to methylphenidate and guanfacine |
| topic | Medicine |
| url | http://hdl.handle.net/11427/12368 |
| work_keys_str_mv | AT hsinwenhsiehjennifer astudyofananimalmodelofattentiondeficithyperactivitydisorderusinginvivochronoamperometryandbehaviouralresponsestomethylphenidateandguanfacine AT hsinwenhsiehjennifer studyofananimalmodelofattentiondeficithyperactivitydisorderusinginvivochronoamperometryandbehaviouralresponsestomethylphenidateandguanfacine |