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Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Medicine
2015
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| _version_ | 1867613239416717312 |
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| access_status_str | Open Access |
| author | Allwood, Brian William |
| author2 | Bateman, Eric D |
| author_browse | Allwood, Brian William Bateman, Eric D |
| author_facet | Bateman, Eric D Allwood, Brian William |
| author_sort | Allwood, Brian William |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12715 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:58.612Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12715 Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease Allwood, Brian William Bateman, Eric D Includes bibliographical references. Epidemiological studies in populations with a high burden of pulmonary tuberculosis (PTB), including the Burden of Obstructive Lung Disease (BOLD) survey performed in Cape Town, South Africa in 2005, have suggested an association between PTB and the development of chronic airflow obstruction (CAO). The nature of this association and mechanisms responsible for CAO has not been previously studied, but likely includes: airway narrowing (from bronchiolitis, bronchiectasis or persistent low-grade inflammation associated with healed PTB); and reduced lung elastic recoil from coexistent emphysema. The present study investigated the structure and function of the lung in subjects with tuberculosis-associated obstructive pulmonary disease (TOPD) identified in BOLD 2005, and aspects of its natural history and response to treatment. It also examined the diagnostic performance of the standardised and internationally accepted BOLD method for estimating the prevalence of COPD in community-based surveys, with specific reference to misdiagnosis that might lead to overestimates of prevalence. 2015-05-04T07:07:44Z 2015-05-04T07:07:44Z 2014 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/12715 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Allwood, Brian William Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease |
| thesis_degree_str | Doctoral |
| title | Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease |
| title_full | Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease |
| title_fullStr | Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease |
| title_full_unstemmed | Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease |
| title_short | Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease |
| title_sort | tuberculosis associated obstructive pulmonary disease a clinical radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community based study of chronic obstructive pulmonary disease |
| url | http://hdl.handle.net/11427/12715 |
| work_keys_str_mv | AT allwoodbrianwilliam tuberculosisassociatedobstructivepulmonarydiseaseaclinicalradiologicalandpathophysiologicalstudyofthecontributionofpreviouspulmonarytuberculosisinacommunitybasedstudyofchronicobstructivepulmonarydisease |