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Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Chemistry
2015
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| _version_ | 1867613206624600064 |
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| access_status_str | Open Access |
| author | Bungane, Ntombovuyo |
| author2 | Rodgers, Allen |
| author_browse | Bungane, Ntombovuyo Rodgers, Allen |
| author_facet | Rodgers, Allen Bungane, Ntombovuyo |
| author_sort | Bungane, Ntombovuyo |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12750 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:27.580Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12750 Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects Bungane, Ntombovuyo Rodgers, Allen Chemistry Includes bibliographical references. In South Africa, the incidence of urolithiasis in the white population occurs to the same extent as in other western societies. However, in the black population, this disease is extremely rare. Differences in the gastrointestinal and renal handling of several lithogenic and antilithogenic agents in the two ethnic groups have been reported, but the rarity of kidney stone disease in the black group remains a riddle. The studies described in this thesis were undertaken to address aspects of this phenomenon. Carbohydrate and oxalate-containing dietary agents were identified as being of interest since surveys have paradoxically demonstrated that the consumption of these potentially lithogenic substances is significantly higher in the black group. The carbohydrates selected for study were glucose, sorbitol and xylitol, while the oxalatecontaining agents were rhubarb, spinach and an aqueous solution of sodium oxalate itself. Finally, taurine, which has been shown to reduce urinary glycolate and oxalate in animal models, was also selected for investigation in the two population groups. In all studies, similar protocols were adopted. These were approved by the Research and Ethics Committee of the University of Cape Town. 2015-05-06T07:18:11Z 2015-05-06T07:18:11Z 2008 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/12750 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town |
| spellingShingle | Chemistry Bungane, Ntombovuyo Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects |
| thesis_degree_str | Doctoral |
| title | Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects |
| title_full | Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects |
| title_fullStr | Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects |
| title_full_unstemmed | Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects |
| title_short | Studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in South African black and white subjects |
| title_sort | studies of the effects of various lithogenic and antilithogenic dietry supplements on calcium oxalate kidney stone risk factors in south african black and white subjects |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/12750 |
| work_keys_str_mv | AT bunganentombovuyo studiesoftheeffectsofvariouslithogenicandantilithogenicdietrysupplementsoncalciumoxalatekidneystoneriskfactorsinsouthafricanblackandwhitesubjects |