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A proteomic investigation of the heat stress response of the South African abalone haliotis midae
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Molecular and Cell Biology
2015
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| _version_ | 1867613181230186496 |
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| access_status_str | Open Access |
| author | Calder, Bridget |
| author2 | Coyne, Vernon |
| author_browse | Calder, Bridget Coyne, Vernon |
| author_facet | Coyne, Vernon Calder, Bridget |
| author_sort | Calder, Bridget |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12756 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:03.909Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Molecular and Cell Biology |
| publisherStr | Department of Molecular and Cell Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12756 A proteomic investigation of the heat stress response of the South African abalone haliotis midae Calder, Bridget Coyne, Vernon Rafudeen, M S Molecular and Cell Biology Includes bibliographical references. The abalone Haliotis midae has been fished to near-extinction on the South African coastline, primarily to satisfy a growing international market. In order to meet demands, H. midae has been produced in South Africa by aquaculture for several decades, and the South African abalone aquaculture industry continues to expand. Internationally, abalone aquaculture has been actively affected by the outbreak of bacterial and viral diseases, which spread rapidly and lead to high abalone mortality. There is evidence that environmental stresses on abalone farms may lead to immunosuppression, and thereby increase the severity of disease outbreaks. The water temperature on abalone farms fluctuates seasonally, and increased abalone mortality has been associated with warmer water during the summer months. However, the molecular mechanisms affecting the abalone during exposure to stress remain unclear. With advances in proteomics technology, it is possible to identify and quantify the expression of several hundred proteins simultaneously. This study therefore aimed to gain insight into the H. midae stress response by using proteomic tools to identify proteins that are differentially regulated in haemocytes during exposure to acute heat stress. Identifying which biochemical pathways are involved in the abalone stress response will give some insight into the molecular mechanism by which H. midae responds to heat stress. 2015-05-06T14:20:19Z 2015-05-06T14:20:19Z 2014 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/12756 eng application/pdf Department of Molecular and Cell Biology Faculty of Science University of Cape Town |
| spellingShingle | Molecular and Cell Biology Calder, Bridget A proteomic investigation of the heat stress response of the South African abalone haliotis midae |
| thesis_degree_str | Doctoral |
| title | A proteomic investigation of the heat stress response of the South African abalone haliotis midae |
| title_full | A proteomic investigation of the heat stress response of the South African abalone haliotis midae |
| title_fullStr | A proteomic investigation of the heat stress response of the South African abalone haliotis midae |
| title_full_unstemmed | A proteomic investigation of the heat stress response of the South African abalone haliotis midae |
| title_short | A proteomic investigation of the heat stress response of the South African abalone haliotis midae |
| title_sort | proteomic investigation of the heat stress response of the south african abalone haliotis midae |
| topic | Molecular and Cell Biology |
| url | http://hdl.handle.net/11427/12756 |
| work_keys_str_mv | AT calderbridget aproteomicinvestigationoftheheatstressresponseofthesouthafricanabalonehaliotismidae AT calderbridget proteomicinvestigationoftheheatstressresponseofthesouthafricanabalonehaliotismidae |