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In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid
Includes bibliographical references.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Chemistry
2015
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| _version_ | 1867614121357213696 |
|---|---|
| access_status_str | Open Access |
| author | Njoroge, Mathew |
| author2 | Chibale, Kelly |
| author_browse | Chibale, Kelly Njoroge, Mathew |
| author_facet | Chibale, Kelly Njoroge, Mathew |
| author_sort | Njoroge, Mathew |
| collection | Thesis |
| description | Includes bibliographical references. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/12928 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:47:00.495Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/12928 In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid Njoroge, Mathew Chibale, Kelly Chemistry Includes bibliographical references. Drug metabolism is recognised as a key component of the drug discovery and development process. It exerts an influence on the action, duration of action and toxicity of a drug in vivo. The integration of drug metabolism studies is therefore crucial to compound progression through the various stages of the development process. This work details the in vitro metabolism work conducted during the early development of aminoquinoline tetrazoles, and derivatives of metergoline and fusidic acid as potential antiplasmodial and/or antimycobacterial agents. 2015-05-27T04:10:48Z 2015-05-27T04:10:48Z 2014 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/12928 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town |
| spellingShingle | Chemistry Njoroge, Mathew In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid |
| thesis_degree_str | Doctoral |
| title | In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid |
| title_full | In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid |
| title_fullStr | In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid |
| title_full_unstemmed | In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid |
| title_short | In vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid |
| title_sort | in vitro metabolism of tetrazole aminoquinolines and derivatives of metergoline and fusidic acid |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/12928 |
| work_keys_str_mv | AT njorogemathew invitrometabolismoftetrazoleaminoquinolinesandderivativesofmetergolineandfusidicacid |