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Venturi aeration of bioreactors

Low solubility of oxygen has resulted in high bioreactor energy requirements in order to supply sufficient oxygen to aerobic bioprocesses. It is desirable to reduce energy consumption in bioreactors to benefit environmental sustainability as well as economic feasibility. This is particularly importa...

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Main Author: Kadzinga, Fadzai
Other Authors: Harrison, STL
Format: Thesis
Language:English
Published: Centre for Bioprocess Engineering Research 2015
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access_status_str Open Access
author Kadzinga, Fadzai
author2 Harrison, STL
author_browse Harrison, STL
Kadzinga, Fadzai
author_facet Harrison, STL
Kadzinga, Fadzai
author_sort Kadzinga, Fadzai
collection Thesis
description Low solubility of oxygen has resulted in high bioreactor energy requirements in order to supply sufficient oxygen to aerobic bioprocesses. It is desirable to reduce energy consumption in bioreactors to benefit environmental sustainability as well as economic feasibility. This is particularly important with the resurgence of interest in bio-based commodity products. Some research has suggested that venturi aeration of bioreactors will reduce energy consumption by eliminating the need for air compression, while at the same time maintaining or improving oxygen transfer rates. On the other hand, there are findings that suggest venturi aeration has lower energy efficiency than conventional sparging and oxygen transfer rates achieved are too low sustain aerobic biological processes. A comparison of the aeration of geometrically-similar reactors using the same analytical methods to determine kLa is not available in the literature. This comparison should also address analysis of energy input including energy used for compressing gas sparged into a stirred tank reactor; the investigation of mass transfer rates at higher flow rates (vvm) in venturi-aerated reactors and resulting cell response to these higher flow rates. This is the topic of the dissertation presented. In this laboratory scale study, venturi aerators were characterised and energy consumption as a function of oxygen mass transfer rates compared with a geometrically identical aerated stirred tank reactor by evaluating the volumetric mass transfer coefficients (kLa). The kLa was investigated in varying reactor setups using the dynamic gassing-in method.
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institution University of Cape Town (South Africa)
language eng
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
publishDateRange 2015
publishDateSort 2015
publisher Centre for Bioprocess Engineering Research
publisherStr Centre for Bioprocess Engineering Research
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/13675 Venturi aeration of bioreactors Kadzinga, Fadzai Harrison, STL Bioprocess Engineering Low solubility of oxygen has resulted in high bioreactor energy requirements in order to supply sufficient oxygen to aerobic bioprocesses. It is desirable to reduce energy consumption in bioreactors to benefit environmental sustainability as well as economic feasibility. This is particularly important with the resurgence of interest in bio-based commodity products. Some research has suggested that venturi aeration of bioreactors will reduce energy consumption by eliminating the need for air compression, while at the same time maintaining or improving oxygen transfer rates. On the other hand, there are findings that suggest venturi aeration has lower energy efficiency than conventional sparging and oxygen transfer rates achieved are too low sustain aerobic biological processes. A comparison of the aeration of geometrically-similar reactors using the same analytical methods to determine kLa is not available in the literature. This comparison should also address analysis of energy input including energy used for compressing gas sparged into a stirred tank reactor; the investigation of mass transfer rates at higher flow rates (vvm) in venturi-aerated reactors and resulting cell response to these higher flow rates. This is the topic of the dissertation presented. In this laboratory scale study, venturi aerators were characterised and energy consumption as a function of oxygen mass transfer rates compared with a geometrically identical aerated stirred tank reactor by evaluating the volumetric mass transfer coefficients (kLa). The kLa was investigated in varying reactor setups using the dynamic gassing-in method. 2015-08-10T06:42:56Z 2015-08-10T06:42:56Z 2015 Master Thesis Masters MSc (Eng) http://hdl.handle.net/11427/13675 eng application/pdf Centre for Bioprocess Engineering Research Faculty of Engineering and the Built Environment University of Cape Town
spellingShingle Bioprocess Engineering
Kadzinga, Fadzai
Venturi aeration of bioreactors
thesis_degree_str Master's
title Venturi aeration of bioreactors
title_full Venturi aeration of bioreactors
title_fullStr Venturi aeration of bioreactors
title_full_unstemmed Venturi aeration of bioreactors
title_short Venturi aeration of bioreactors
title_sort venturi aeration of bioreactors
topic Bioprocess Engineering
url http://hdl.handle.net/11427/13675
work_keys_str_mv AT kadzingafadzai venturiaerationofbioreactors