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HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes

Background Sentinel antenatal clinic (ANC) surveys remain a key source of data on HIV prevalence trends. Recently though, with an increase in the uptake of prevention of mother-to-child transmission (PMTCT) programmes, there have been debates on the prospects of using PMTCT data for reporting antena...

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Main Author: Essel, Vivien
Other Authors: Boulle, Andrew
Format: Thesis
Language:English
Published: Department of Public Health and Family Medicine 2015
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access_status_str Open Access
author Essel, Vivien
author2 Boulle, Andrew
author_browse Boulle, Andrew
Essel, Vivien
author_facet Boulle, Andrew
Essel, Vivien
author_sort Essel, Vivien
collection Thesis
description Background Sentinel antenatal clinic (ANC) surveys remain a key source of data on HIV prevalence trends. Recently though, with an increase in the uptake of prevention of mother-to-child transmission (PMTCT) programmes, there have been debates on the prospects of using PMTCT data for reporting antenatal HIV prevalence and trends. Aim To describe the HIV prevalence trends for the Western Cape Province and to compare prevalence from ANC surveys to PMTCT programmes. Methods HIV prevalence and 95% confidence intervals were estimated from ANC surveys from 2001-2012 for the province as well as the 6 health districts and the 8 City of Cape Town Metropolitan sub-districts in the province. HIV prevalence from expanded provincial ANC survey sampling was compared to the nationally reported provincial and district estimates, before and after re-weighting to account for differences between the realized sample and updated sampling frame. A regression line was fitted with calendar year included as both a linear and quadratic term to create smoothed trend lines of the change in HIV prevalence over time by province, district, sub-district and age group. A multivariable logistic regression model was fitted to the multi-year ANC survey data to explore associations with HIV prevalence. ANC survey HIV prevalence estimates were compared to those from routinely reported HIV testing data from the PMTCT program for 2009-2012.
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license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
publishDateRange 2015
publishDateSort 2015
publisher Department of Public Health and Family Medicine
publisherStr Department of Public Health and Family Medicine
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/13804 HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes Essel, Vivien Boulle, Andrew Pienaar, David Public Health Background Sentinel antenatal clinic (ANC) surveys remain a key source of data on HIV prevalence trends. Recently though, with an increase in the uptake of prevention of mother-to-child transmission (PMTCT) programmes, there have been debates on the prospects of using PMTCT data for reporting antenatal HIV prevalence and trends. Aim To describe the HIV prevalence trends for the Western Cape Province and to compare prevalence from ANC surveys to PMTCT programmes. Methods HIV prevalence and 95% confidence intervals were estimated from ANC surveys from 2001-2012 for the province as well as the 6 health districts and the 8 City of Cape Town Metropolitan sub-districts in the province. HIV prevalence from expanded provincial ANC survey sampling was compared to the nationally reported provincial and district estimates, before and after re-weighting to account for differences between the realized sample and updated sampling frame. A regression line was fitted with calendar year included as both a linear and quadratic term to create smoothed trend lines of the change in HIV prevalence over time by province, district, sub-district and age group. A multivariable logistic regression model was fitted to the multi-year ANC survey data to explore associations with HIV prevalence. ANC survey HIV prevalence estimates were compared to those from routinely reported HIV testing data from the PMTCT program for 2009-2012. 2015-08-27T12:36:00Z 2015-08-27T12:36:00Z 2015 Master Thesis Masters MMed http://hdl.handle.net/11427/13804 eng application/pdf Department of Public Health and Family Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Public Health
Essel, Vivien
HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes
thesis_degree_str Master's
title HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes
title_full HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes
title_fullStr HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes
title_full_unstemmed HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes
title_short HIV surveillance : a 12 year analysis of HIV prevalence trends and comparing HIV prevalence from sentinel antenatal clinic surveys and prevention of mother-to-child programmes
title_sort hiv surveillance a 12 year analysis of hiv prevalence trends and comparing hiv prevalence from sentinel antenatal clinic surveys and prevention of mother to child programmes
topic Public Health
url http://hdl.handle.net/11427/13804
work_keys_str_mv AT esselvivien hivsurveillancea12yearanalysisofhivprevalencetrendsandcomparinghivprevalencefromsentinelantenatalclinicsurveysandpreventionofmothertochildprogrammes