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The role of propranolol in the treatment of infantile haemangioma
There has been a change in the management of infantile haemangioma with the introduction of propranolol. The aim of this study is to retrospectively evaluate a simple treatment for infantile haemangioma at the Red Cross War Memorial Children’s Hospital (RCWMCH) and document the results. While it i...
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| Format: | Thesis |
| Language: | English |
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Division of Plastic and Reconstructive Surgery
2015
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| _version_ | 1867613235341950976 |
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| access_status_str | Open Access |
| author | Moodley, Sean Thirumalay |
| author2 | Hudson, Donald |
| author_browse | Hudson, Donald Moodley, Sean Thirumalay |
| author_facet | Hudson, Donald Moodley, Sean Thirumalay |
| author_sort | Moodley, Sean Thirumalay |
| collection | Thesis |
| description | There has been a change in the management of infantile haemangioma with the introduction of propranolol. The aim of this study is to retrospectively evaluate a simple treatment for infantile haemangioma at the Red Cross War Memorial Children’s Hospital (RCWMCH) and document the results. While it is known that all haemangiomas undergo involution at some stage, some haemangiomas pose certain problems. These relate mainly to visual axis obstruction and aesthetics. Subjects are children in the first two years of life presenting with haemangiomas. All patients were treated with oral propranolol in conjunction with haemangioma size documentation, using a simple radiological modality, i.e. ultrasound imaging. Patients are followed up and clinical and radiological evaluations are undertaken to observe changes in size and appearance. Propranolol is non-selective β-adrenergic antagonist that is used extensively for the treatment of a multitude of disorders, mainly cardiovascular indications. The main adverse effects include bradycardia, hypotension and bronchospasms. For the purposes of this study, all subjects were routinely examined, especially with regard to the cardiopulmonary systems. Any perceived anomaly was referred to the cardiorespiratory physicians at RCWMCH for further evaluation, which includes all the necessary investigations such as electrocardiograms(ECG) and echocardiograms. Therefore, only fit healthy patients were selected for this study. Patients are educated and fully informed regarding the adverse effect profile of propranolol, and advised of the appropriate route of management. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/13923 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:54.720Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Plastic and Reconstructive Surgery |
| publisherStr | Division of Plastic and Reconstructive Surgery |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/13923 The role of propranolol in the treatment of infantile haemangioma Moodley, Sean Thirumalay Hudson, Donald Plastic and Reconstructive Surgery There has been a change in the management of infantile haemangioma with the introduction of propranolol. The aim of this study is to retrospectively evaluate a simple treatment for infantile haemangioma at the Red Cross War Memorial Children’s Hospital (RCWMCH) and document the results. While it is known that all haemangiomas undergo involution at some stage, some haemangiomas pose certain problems. These relate mainly to visual axis obstruction and aesthetics. Subjects are children in the first two years of life presenting with haemangiomas. All patients were treated with oral propranolol in conjunction with haemangioma size documentation, using a simple radiological modality, i.e. ultrasound imaging. Patients are followed up and clinical and radiological evaluations are undertaken to observe changes in size and appearance. Propranolol is non-selective β-adrenergic antagonist that is used extensively for the treatment of a multitude of disorders, mainly cardiovascular indications. The main adverse effects include bradycardia, hypotension and bronchospasms. For the purposes of this study, all subjects were routinely examined, especially with regard to the cardiopulmonary systems. Any perceived anomaly was referred to the cardiorespiratory physicians at RCWMCH for further evaluation, which includes all the necessary investigations such as electrocardiograms(ECG) and echocardiograms. Therefore, only fit healthy patients were selected for this study. Patients are educated and fully informed regarding the adverse effect profile of propranolol, and advised of the appropriate route of management. 2015-09-15T10:06:09Z 2015-09-15T10:06:09Z 2013 Master Thesis Masters MMed http://hdl.handle.net/11427/13923 eng application/pdf Division of Plastic and Reconstructive Surgery Faculty of Health Sciences University of Cape Town |
| spellingShingle | Plastic and Reconstructive Surgery Moodley, Sean Thirumalay The role of propranolol in the treatment of infantile haemangioma |
| thesis_degree_str | Master's |
| title | The role of propranolol in the treatment of infantile haemangioma |
| title_full | The role of propranolol in the treatment of infantile haemangioma |
| title_fullStr | The role of propranolol in the treatment of infantile haemangioma |
| title_full_unstemmed | The role of propranolol in the treatment of infantile haemangioma |
| title_short | The role of propranolol in the treatment of infantile haemangioma |
| title_sort | role of propranolol in the treatment of infantile haemangioma |
| topic | Plastic and Reconstructive Surgery |
| url | http://hdl.handle.net/11427/13923 |
| work_keys_str_mv | AT moodleyseanthirumalay theroleofpropranololinthetreatmentofinfantilehaemangioma AT moodleyseanthirumalay roleofpropranololinthetreatmentofinfantilehaemangioma |