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Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial

Background The timeous achievement of full enteral nutrition in a preterm infant is a critical prerequisite for optimal growth, neurodevelopment and long-term wellbeing. However, the optimal enteral feeding regimen for preterm infants has not been established, and wide variations occur in practice....

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Main Author: Raban, Moegammad Shukri
Other Authors: Harrison, Michael C
Format: Thesis
Language:English
Published: Department of Paediatrics and Child Health 2015
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access_status_str Open Access
author Raban, Moegammad Shukri
author2 Harrison, Michael C
author_browse Harrison, Michael C
Raban, Moegammad Shukri
author_facet Harrison, Michael C
Raban, Moegammad Shukri
author_sort Raban, Moegammad Shukri
collection Thesis
description Background The timeous achievement of full enteral nutrition in a preterm infant is a critical prerequisite for optimal growth, neurodevelopment and long-term wellbeing. However, the optimal enteral feeding regimen for preterm infants has not been established, and wide variations occur in practice. The debate on the most appropriate feeding strategy is nuanced by studies suggesting that early introduction of enteral feeds and the rapid advancement of enteral feeds may increase the risk of feeding intolerance and may be involved in the pathogenesis of necrotising enterocolitis (NEC). Objective 1. To review randomised controlled trials (RCT); examining the effect that the rate of advancement of enteral feeds has on the incidence of; NEC, mortality, growth, health care utilisation and other morbidities in very low birth weight (VLBW) and extremely low birth weight (ELBW) infants. 2. To establish the safety and efficacy of commencing enteral breast milk feeds at 24 ml/kg/day on the day of birth and advancing enteral breast milk feeds at 36 ml/kg/day, in infants weighing ≤ 1000 g.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:48:42.818Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
publishDateRange 2015
publishDateSort 2015
publisher Department of Paediatrics and Child Health
publisherStr Department of Paediatrics and Child Health
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/13973 Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial Raban, Moegammad Shukri Harrison, Michael C Horn, Alan R Modi, Neena Neonatology Background The timeous achievement of full enteral nutrition in a preterm infant is a critical prerequisite for optimal growth, neurodevelopment and long-term wellbeing. However, the optimal enteral feeding regimen for preterm infants has not been established, and wide variations occur in practice. The debate on the most appropriate feeding strategy is nuanced by studies suggesting that early introduction of enteral feeds and the rapid advancement of enteral feeds may increase the risk of feeding intolerance and may be involved in the pathogenesis of necrotising enterocolitis (NEC). Objective 1. To review randomised controlled trials (RCT); examining the effect that the rate of advancement of enteral feeds has on the incidence of; NEC, mortality, growth, health care utilisation and other morbidities in very low birth weight (VLBW) and extremely low birth weight (ELBW) infants. 2. To establish the safety and efficacy of commencing enteral breast milk feeds at 24 ml/kg/day on the day of birth and advancing enteral breast milk feeds at 36 ml/kg/day, in infants weighing ≤ 1000 g. 2015-09-15T10:25:18Z 2015-09-15T10:25:18Z 2014 Master Thesis Masters MPhil http://hdl.handle.net/11427/13973 eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences University of Cape Town
spellingShingle Neonatology
Raban, Moegammad Shukri
Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial
thesis_degree_str Master's
title Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial
title_full Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial
title_fullStr Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial
title_full_unstemmed Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial
title_short Rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants < 1000g: randomised controlled trial
title_sort rapid versus slow rate advancement of feeds for enterally fed extremely low birth weight infants 1000g randomised controlled trial
topic Neonatology
url http://hdl.handle.net/11427/13973
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