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Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa

Acinetobacter baumannii (A. baumannii) is now increasingly recognised as an important cause of nosocomial infections in paediatric intensive care unit (PICU) patients, particularly in developing countries, where it contributes significantly to morbidity and mortality. Furthermore, it has been docume...

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Main Author: Reddy, Deveshnee
Other Authors: Argent, Andrew
Format: Thesis
Language:English
Published: Department of Paediatrics and Child Health 2015
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access_status_str Open Access
author Reddy, Deveshnee
author2 Argent, Andrew
author_browse Argent, Andrew
Reddy, Deveshnee
author_facet Argent, Andrew
Reddy, Deveshnee
author_sort Reddy, Deveshnee
collection Thesis
description Acinetobacter baumannii (A. baumannii) is now increasingly recognised as an important cause of nosocomial infections in paediatric intensive care unit (PICU) patients, particularly in developing countries, where it contributes significantly to morbidity and mortality. Furthermore, it has been documented that emerging antimicrobial resistance patterns complicate antibiotic choice in these patients. At present, more paediatric data is needed regarding these infections. This is a retrospective case-control study that aims to document the demographic data and relevant clinical details of patients in whom A. baumannii was cultured, either from blood or respiratory specimens (thus including both infections and colonisation), in the PICU at Red Cross War Memorial Children's Hospital (RCWMCH) during 2010. Secondary objectives include comparing these patients with those in whom A. baumannii was not cultured and determining which isolates were causing infection and which were colonisers. In addition; of the isolates regarded as infections, documenting the antimicrobial sensitivities and resistance of the organisms cultured, determining whether infections were late or early onset and determining whether specific bed numbers were consistently involved.
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provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2015
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spelling oai:open.uct.ac.za:11427/13974 Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa Reddy, Deveshnee Argent, Andrew Morrow, Brenda M Paediatrics Acinetobacter baumannii (A. baumannii) is now increasingly recognised as an important cause of nosocomial infections in paediatric intensive care unit (PICU) patients, particularly in developing countries, where it contributes significantly to morbidity and mortality. Furthermore, it has been documented that emerging antimicrobial resistance patterns complicate antibiotic choice in these patients. At present, more paediatric data is needed regarding these infections. This is a retrospective case-control study that aims to document the demographic data and relevant clinical details of patients in whom A. baumannii was cultured, either from blood or respiratory specimens (thus including both infections and colonisation), in the PICU at Red Cross War Memorial Children's Hospital (RCWMCH) during 2010. Secondary objectives include comparing these patients with those in whom A. baumannii was not cultured and determining which isolates were causing infection and which were colonisers. In addition; of the isolates regarded as infections, documenting the antimicrobial sensitivities and resistance of the organisms cultured, determining whether infections were late or early onset and determining whether specific bed numbers were consistently involved. 2015-09-15T10:25:29Z 2015-09-15T10:25:29Z 2014 Master Thesis Masters MMed http://hdl.handle.net/11427/13974 eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences University of Cape Town
spellingShingle Paediatrics
Reddy, Deveshnee
Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa
thesis_degree_str Master's
title Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa
title_full Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa
title_fullStr Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa
title_full_unstemmed Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa
title_short Acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in South Africa
title_sort acinetobacter baumannii infections in the paediatric intensive care unit of a tertiary hospital in south africa
topic Paediatrics
url http://hdl.handle.net/11427/13974
work_keys_str_mv AT reddydeveshnee acinetobacterbaumanniiinfectionsinthepaediatricintensivecareunitofatertiaryhospitalinsouthafrica