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Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation
Includes bibliographical references (leaves [184]-205).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Department of Chemistry
2015
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| _version_ | 1867613252045766656 |
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| access_status_str | Open Access |
| author | Mabizela, Nontobeko |
| author2 | Rodgers, Allen |
| author_browse | Mabizela, Nontobeko Rodgers, Allen |
| author_facet | Rodgers, Allen Mabizela, Nontobeko |
| author_sort | Mabizela, Nontobeko |
| collection | Thesis |
| description | Includes bibliographical references (leaves [184]-205). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/14033 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:10.259Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Department of Chemistry |
| publisherStr | Department of Chemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/14033 Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation Mabizela, Nontobeko Rodgers, Allen Sturrock, Edward D Chemistry Includes bibliographical references (leaves [184]-205). Approximately 12 % of males in the Western world are likely to suffer at least one kidney stone in their life. The incidence of kidney stone disease in South Africa is similar in white males; however stone occurrence in the South African black population is extremely rare. The difference between the incidences of kidney stones in the black and white populations in South Africa is unexplained. In general, the role of several urinary proteins in the pathogenesis of this disease has been established. Bikunin is an example. The primary aim of this study was to isolate bikunin from the urine of healthy black and white male subjects and to investigate whether the protein from the black group is a more powerful inhibitor of CaOx crystallization than that from the stone prone white group. 2015-09-15T10:33:50Z 2015-09-15T10:33:50Z 2006 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/14033 eng application/pdf Department of Chemistry Faculty of Science University of Cape Town |
| spellingShingle | Chemistry Mabizela, Nontobeko Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation |
| thesis_degree_str | Doctoral |
| title | Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation |
| title_full | Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation |
| title_fullStr | Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation |
| title_full_unstemmed | Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation |
| title_short | Characterization of the physiochemical and biochemical properties of the urinary protein bikunin in South African black and white subjects with respect to calcium oxalate kidney stone formation |
| title_sort | characterization of the physiochemical and biochemical properties of the urinary protein bikunin in south african black and white subjects with respect to calcium oxalate kidney stone formation |
| topic | Chemistry |
| url | http://hdl.handle.net/11427/14033 |
| work_keys_str_mv | AT mabizelanontobeko characterizationofthephysiochemicalandbiochemicalpropertiesoftheurinaryproteinbikunininsouthafricanblackandwhitesubjectswithrespecttocalciumoxalatekidneystoneformation |