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Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population
Statement of problem: Topical corticosteroids nasal sprays remain first line of treatment for patients with chronic rhinosinusitis (with or without nasal polyps). The main aim of treatment is to improve nasal symptoms by reducing or eliminating the nasal polyps and preventing polyp recurrence post-o...
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Division of Otorhinolaryngology
2015
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| _version_ | 1867613772128976896 |
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| access_status_str | Open Access |
| author | Monteiro, Pedro Vilas Boas |
| author2 | Lubbe, Darlene |
| author_browse | Lubbe, Darlene Monteiro, Pedro Vilas Boas |
| author_facet | Lubbe, Darlene Monteiro, Pedro Vilas Boas |
| author_sort | Monteiro, Pedro Vilas Boas |
| collection | Thesis |
| description | Statement of problem: Topical corticosteroids nasal sprays remain first line of treatment for patients with chronic rhinosinusitis (with or without nasal polyps). The main aim of treatment is to improve nasal symptoms by reducing or eliminating the nasal polyps and preventing polyp recurrence post-operatively. Our aims were to determine if the type of corticosteroid nasal spray used post operatively influences polyp recurrence rate and if there were any subsequent economic implications as we only have beclomethasone available for prescription in our state hospital. Methods: Retrospective case note review of all Samter's patients who underwent fronto-spheno-ethmoidectomy by a single surgeon (2000 – 2014). Results: 58 patients were included in our study, divided into 3 study groups. When compared to patients using beclomethasone; patients using fluticasone had an 80% reduced risk of polyp recurrence and patients using mometasone a 90% reduced risk. This rose to 88% and 96% respectively when adjusted for age. Conclusion: Fluticasone and mometasone are both statistically significantly more effective at reducing polyp recurrence than beclomethasone in our population group. Mometasone appeared more effective than fluticasone, but this difference was not statistically significant. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/15753 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:41:27.446Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2015 |
| publishDateRange | 2015 |
| publishDateSort | 2015 |
| publisher | Division of Otorhinolaryngology |
| publisherStr | Division of Otorhinolaryngology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/15753 Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population Monteiro, Pedro Vilas Boas Lubbe, Darlene Otorhinolaryngology Statement of problem: Topical corticosteroids nasal sprays remain first line of treatment for patients with chronic rhinosinusitis (with or without nasal polyps). The main aim of treatment is to improve nasal symptoms by reducing or eliminating the nasal polyps and preventing polyp recurrence post-operatively. Our aims were to determine if the type of corticosteroid nasal spray used post operatively influences polyp recurrence rate and if there were any subsequent economic implications as we only have beclomethasone available for prescription in our state hospital. Methods: Retrospective case note review of all Samter's patients who underwent fronto-spheno-ethmoidectomy by a single surgeon (2000 – 2014). Results: 58 patients were included in our study, divided into 3 study groups. When compared to patients using beclomethasone; patients using fluticasone had an 80% reduced risk of polyp recurrence and patients using mometasone a 90% reduced risk. This rose to 88% and 96% respectively when adjusted for age. Conclusion: Fluticasone and mometasone are both statistically significantly more effective at reducing polyp recurrence than beclomethasone in our population group. Mometasone appeared more effective than fluticasone, but this difference was not statistically significant. 2015-12-10T09:30:15Z 2015-12-10T09:30:15Z 2015 Master Thesis Masters MMed http://hdl.handle.net/11427/15753 eng application/pdf Division of Otorhinolaryngology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Otorhinolaryngology Monteiro, Pedro Vilas Boas Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population |
| thesis_degree_str | Master's |
| title | Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population |
| title_full | Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population |
| title_fullStr | Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population |
| title_full_unstemmed | Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population |
| title_short | Comparing the efficiency of beclomethasone, fluticasone and mometasone nasal sprays in a Samter's population |
| title_sort | comparing the efficiency of beclomethasone fluticasone and mometasone nasal sprays in a samter s population |
| topic | Otorhinolaryngology |
| url | http://hdl.handle.net/11427/15753 |
| work_keys_str_mv | AT monteiropedrovilasboas comparingtheefficiencyofbeclomethasonefluticasoneandmometasonenasalspraysinasamterspopulation |