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Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country
Includes bibliographical references
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Paediatrics and Child Health
2016
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| _version_ | 1867613332090912768 |
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| access_status_str | Open Access |
| author | Appiah, John Adabie |
| author2 | Argent, Andrew |
| author_browse | Appiah, John Adabie Argent, Andrew |
| author_facet | Argent, Andrew Appiah, John Adabie |
| author_sort | Appiah, John Adabie |
| collection | Thesis |
| description | Includes bibliographical references |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/16433 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:27.383Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2016 |
| publishDateRange | 2016 |
| publishDateSort | 2016 |
| publisher | Department of Paediatrics and Child Health |
| publisherStr | Department of Paediatrics and Child Health |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/16433 Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country Appiah, John Adabie Argent, Andrew Salie, Shamiel Critical Care Paediatrics Includes bibliographical references Objective: To describe the characteristics and outcomes of children admitted to PICU following cardiac arrest between January 2010 and December 2011. Methods: Retrospective descriptive study of routinely collected data. Results: Of 2501 PICU admissions, 110 (4.4%; 58.7% male) had preceding cardiac arrest, 80.6% of which occurred in hospital. Median (IQR) age was 7.2 (2.5 - 21.6) months; 30.8% had chronic underlying disease. Children presented most commonly with respiratory (n=28, 27.2%), cardiovascular (n= 22, 21.4%), and gastrointestinal disease (n= 20, 19.4%). Twenty-eight (27.2%) arrested while undergoing a procedure. Cardiopulmonary resuscitation (CPR) was given for median (IQR) 10 (5 - 20) minutes. Thirty-five (34%) patients received no adrenaline, 44 (42.7%) received up to 3 doses of adrenaline, and 24 (23.3%) received more than 3 doses of adrenaline during resuscitation. Duration of CPR and number of adrenaline doses did not significantly influence patient outcome. Survival to PICU discharge was 63 (61.2%), 57 (55.3%) survived to hospital discharge with half the deaths in PICU occurred within 24 hours of PICU admission. Out of 51 survivors whose neurological status were assessed 32 were normal, 6 had mild disability, 7 had moderate disability and 6 had severe disability. Standardized mortality ratio (actual/mean predicted) was 0.7. The median (IQR) length of stay in PICU and hospital were 3 (1 - 8) and 27 (9 -52) days respectively. Pediatric risk of mortality (PIM2) score was the only variable independently associated with mortality on multiple logistic regression (adjusted OR 1.05; 95% CI 1.02 - 1.07; p=0.0009). 2016-01-19T12:15:43Z 2016-01-19T12:15:43Z 2015 Master Thesis Masters MPhil http://hdl.handle.net/11427/16433 eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences University of Cape Town |
| spellingShingle | Critical Care Paediatrics Appiah, John Adabie Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country |
| thesis_degree_str | Master's |
| title | Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country |
| title_full | Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country |
| title_fullStr | Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country |
| title_full_unstemmed | Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country |
| title_short | Cardiac arrest in children preceding PICU admission: Aetiology and outcome in a developing country |
| title_sort | cardiac arrest in children preceding picu admission aetiology and outcome in a developing country |
| topic | Critical Care Paediatrics |
| url | http://hdl.handle.net/11427/16433 |
| work_keys_str_mv | AT appiahjohnadabie cardiacarrestinchildrenprecedingpicuadmissionaetiologyandoutcomeinadevelopingcountry |