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Adherence in HIV-positive women entering antenatal care on antiretroviral therapy: A cross-sectional study

Includes bibliographical references

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Bibliographic Details
Main Author: O'Sullivan, Briana Jean
Other Authors: Myer, Landon
Format: Thesis
Language:English
Published: Department of Public Health and Family Medicine 2016
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access_status_str Open Access
author O'Sullivan, Briana Jean
author2 Myer, Landon
author_browse Myer, Landon
O'Sullivan, Briana Jean
author_facet Myer, Landon
O'Sullivan, Briana Jean
author_sort O'Sullivan, Briana Jean
collection Thesis
description Includes bibliographical references
format Thesis
id oai:open.uct.ac.za:11427/16701
institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:32:41.376Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2016
publishDateRange 2016
publishDateSort 2016
publisher Department of Public Health and Family Medicine
publisherStr Department of Public Health and Family Medicine
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/16701 Adherence in HIV-positive women entering antenatal care on antiretroviral therapy: A cross-sectional study O'Sullivan, Briana Jean Myer, Landon Public Health HIV Infections Pregnancy Reproductive Health Antenatal Care Includes bibliographical references Proper implementation of and adherence to antiretroviral therapy (ART) is significantly associated with better health and longer life in HIV-positive individuals. Consistent, adequate adherence has been shown to lead to a suppressed viral load. A low viral load delays the virus's progression and leads to better health outcomes for the individual. Adequate adherence is especially important among HIV-positive pregnant women. How well a woman adheres to her ART can not only improve her health during pregnancy but can protect the infant from HIV by preventing in utero transmission of the virus. Continuing ART protects against transmission via breastmilk later in the infant's life. While the benefits of good adherence are undeniable, the definition of adequate adherence varies widely in the literature. Taking 80 to 100% of pills as prescribed is commonly used as the threshold for adequate adherence levels. Various methods exist for measuring ART adherence, and while some are more reliable than others, there is no gold standard. This ambiguity in ART research extends to pregnant women, with even less known about HIV infected women established already on ART who then become pregnant. Changes in treatment protocols in the Western Cape and improvement of ART delivery throughout South Africa have resulted in this group of long-term users growing in size. Without more research into the barriers of ART adherence in these women, efforts to scale up treatment programs and to end mother to child transmission of HIV will ultimately fail. This dissertation is an exploration of these ideas. It begins to fill the gap in current knowledge related to ART compliance in pregnant women, and gives new insights into how specific barriers to adherence can adversely affect this specific group of established ART users. 2016-02-02T14:43:14Z 2016-02-02T14:43:14Z 2015 Master Thesis Masters MPH http://hdl.handle.net/11427/16701 eng application/pdf Department of Public Health and Family Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Public Health
HIV Infections
Pregnancy
Reproductive Health
Antenatal Care
O'Sullivan, Briana Jean
Adherence in HIV-positive women entering antenatal care on antiretroviral therapy: A cross-sectional study
thesis_degree_str Master's
title Adherence in HIV-positive women entering antenatal care on antiretroviral therapy: A cross-sectional study
title_full Adherence in HIV-positive women entering antenatal care on antiretroviral therapy: A cross-sectional study
title_fullStr Adherence in HIV-positive women entering antenatal care on antiretroviral therapy: A cross-sectional study
title_full_unstemmed Adherence in HIV-positive women entering antenatal care on antiretroviral therapy: A cross-sectional study
title_short Adherence in HIV-positive women entering antenatal care on antiretroviral therapy: A cross-sectional study
title_sort adherence in hiv positive women entering antenatal care on antiretroviral therapy a cross sectional study
topic Public Health
HIV Infections
Pregnancy
Reproductive Health
Antenatal Care
url http://hdl.handle.net/11427/16701
work_keys_str_mv AT osullivanbrianajean adherenceinhivpositivewomenenteringantenatalcareonantiretroviraltherapyacrosssectionalstudy