Full Text Available
Note: Clicking the button above will open the full text document at the original institutional repository in a new window.
Evaluation of diagnostic advances in musculoskeletal tuberculosis; the automated xpert MTB/RIF assay
The aim of this thesis was to investigate the diagnostic accuracy of Xpert for musculoskeletal TB and for rifampicin resistance against a gold standard of culture or histology. Site of disease, HIV status, and age of patients, and accuracy in spinal compared to extraspinal TB were investigated as se...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Health and Rehabilitation Sciences
2016
|
| Subjects: | |
| Tags: |
No Tags, Be the first to tag this record!
|
| _version_ | 1867613236678885376 |
|---|---|
| access_status_str | Open Access |
| author | Held, Michael |
| author2 | Zar, Heather |
| author_browse | Held, Michael Zar, Heather |
| author_facet | Zar, Heather Held, Michael |
| author_sort | Held, Michael |
| collection | Thesis |
| description | The aim of this thesis was to investigate the diagnostic accuracy of Xpert for musculoskeletal TB and for rifampicin resistance against a gold standard of culture or histology. Site of disease, HIV status, and age of patients, and accuracy in spinal compared to extraspinal TB were investigated as secondary objectives. The overarching hypothesis was that Xpert is more accurate and would provide results faster than the gold standard for musculoskeletal TB, and that it would have a higher yield in HIV infected patients, adult patients, and patients with spinal disease. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/20495 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:56.154Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2016 |
| publishDateRange | 2016 |
| publishDateSort | 2016 |
| publisher | Department of Health and Rehabilitation Sciences |
| publisherStr | Department of Health and Rehabilitation Sciences |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/20495 Evaluation of diagnostic advances in musculoskeletal tuberculosis; the automated xpert MTB/RIF assay Held, Michael Zar, Heather Dunn, Robert Orthopaedic Surgery The aim of this thesis was to investigate the diagnostic accuracy of Xpert for musculoskeletal TB and for rifampicin resistance against a gold standard of culture or histology. Site of disease, HIV status, and age of patients, and accuracy in spinal compared to extraspinal TB were investigated as secondary objectives. The overarching hypothesis was that Xpert is more accurate and would provide results faster than the gold standard for musculoskeletal TB, and that it would have a higher yield in HIV infected patients, adult patients, and patients with spinal disease. 2016-07-20T06:59:37Z 2016-07-20T06:59:37Z 2016 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/20495 eng application/pdf Department of Health and Rehabilitation Sciences Faculty of Health Sciences University of Cape Town |
| spellingShingle | Orthopaedic Surgery Held, Michael Evaluation of diagnostic advances in musculoskeletal tuberculosis; the automated xpert MTB/RIF assay |
| thesis_degree_str | Doctoral |
| title | Evaluation of diagnostic advances in musculoskeletal tuberculosis; the automated xpert MTB/RIF assay |
| title_full | Evaluation of diagnostic advances in musculoskeletal tuberculosis; the automated xpert MTB/RIF assay |
| title_fullStr | Evaluation of diagnostic advances in musculoskeletal tuberculosis; the automated xpert MTB/RIF assay |
| title_full_unstemmed | Evaluation of diagnostic advances in musculoskeletal tuberculosis; the automated xpert MTB/RIF assay |
| title_short | Evaluation of diagnostic advances in musculoskeletal tuberculosis; the automated xpert MTB/RIF assay |
| title_sort | evaluation of diagnostic advances in musculoskeletal tuberculosis the automated xpert mtb rif assay |
| topic | Orthopaedic Surgery |
| url | http://hdl.handle.net/11427/20495 |
| work_keys_str_mv | AT heldmichael evaluationofdiagnosticadvancesinmusculoskeletaltuberculosistheautomatedxpertmtbrifassay |