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The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha

Summary: There is strong evidence suggesting that diabetes mellitus (DM) triples the risk of tuberculosis (TB) disease and worsens TB outcomes. South Africa carries a heavy burden of TB which is primarily driven by the human deficiency virus (HIV). The burden of non-communicable disease is also grow...

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Main Author: Kubjane, Mmamapudi
Other Authors: Oni, Tolullah
Format: Thesis
Language:English
Published: Institute of Infectious Disease and Molecular Medicine 2016
Subjects:
Epidemiology
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access_status_str Open Access
author Kubjane, Mmamapudi
author2 Oni, Tolullah
author_browse Kubjane, Mmamapudi
Oni, Tolullah
author_facet Oni, Tolullah
Kubjane, Mmamapudi
author_sort Kubjane, Mmamapudi
collection Thesis
description Summary: There is strong evidence suggesting that diabetes mellitus (DM) triples the risk of tuberculosis (TB) disease and worsens TB outcomes. South Africa carries a heavy burden of TB which is primarily driven by the human deficiency virus (HIV). The burden of non-communicable disease is also growing rapidly in South Africa. There is however lack of up to date data on the burden of DM and the associated risk factors among TB patients. This dissertation is based on a cross-sectional study which sought to assess the prevalence of DM and impaired glucose tolerance (IGT) and determine the risk factors associated with DM among TB patients. Methods: This cross sectional study forms part of a case control study that aimed to assess the association between DM and TB and the population attributable risk of TB due to DM in Khayelitsha, a high HIV and TB setting. The TB patients recruited in the case control study formed the population of this current cross-sectional study. Based on oral glucose tolerance test, fasting blood glucose, glycated haemoglobin and self-report the prevalence of DM was determined. Bivariate and multivariate logistic regression analyses were performed to assess risk factors associated DM among TB patients. Due to significant differences between male and females with respect to various characteristics, we also stratified the data by sex during analysis.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:31:52.071Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2016
publishDateRange 2016
publishDateSort 2016
publisher Institute of Infectious Disease and Molecular Medicine
publisherStr Institute of Infectious Disease and Molecular Medicine
record_format dspace
source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/20523 The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha Kubjane, Mmamapudi Oni, Tolullah Epidemiology Summary: There is strong evidence suggesting that diabetes mellitus (DM) triples the risk of tuberculosis (TB) disease and worsens TB outcomes. South Africa carries a heavy burden of TB which is primarily driven by the human deficiency virus (HIV). The burden of non-communicable disease is also growing rapidly in South Africa. There is however lack of up to date data on the burden of DM and the associated risk factors among TB patients. This dissertation is based on a cross-sectional study which sought to assess the prevalence of DM and impaired glucose tolerance (IGT) and determine the risk factors associated with DM among TB patients. Methods: This cross sectional study forms part of a case control study that aimed to assess the association between DM and TB and the population attributable risk of TB due to DM in Khayelitsha, a high HIV and TB setting. The TB patients recruited in the case control study formed the population of this current cross-sectional study. Based on oral glucose tolerance test, fasting blood glucose, glycated haemoglobin and self-report the prevalence of DM was determined. Bivariate and multivariate logistic regression analyses were performed to assess risk factors associated DM among TB patients. Due to significant differences between male and females with respect to various characteristics, we also stratified the data by sex during analysis. 2016-07-20T12:25:52Z 2016-07-20T12:25:52Z 2016 Master Thesis Masters MPH http://hdl.handle.net/11427/20523 eng application/pdf Institute of Infectious Disease and Molecular Medicine Faculty of Health Sciences University of Cape Town
spellingShingle Epidemiology
Kubjane, Mmamapudi
The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha
thesis_degree_str Master's
title The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha
title_full The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha
title_fullStr The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha
title_full_unstemmed The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha
title_short The prevalence and risk factors of diabetes mellitus among tuberculosis patients at Ubuntu clinic, Khayelitsha
title_sort prevalence and risk factors of diabetes mellitus among tuberculosis patients at ubuntu clinic khayelitsha
topic Epidemiology
url http://hdl.handle.net/11427/20523
work_keys_str_mv AT kubjanemmamapudi theprevalenceandriskfactorsofdiabetesmellitusamongtuberculosispatientsatubuntuclinickhayelitsha
AT kubjanemmamapudi prevalenceandriskfactorsofdiabetesmellitusamongtuberculosispatientsatubuntuclinickhayelitsha

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