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The impact of myeloid derived suppressor cells on vaccine immunogenicity in South African HIV-infected and uninfected mothers and their infants

BACKGROUND: Each year over 4 million infants die from infections, of which many are vaccinepreventable. Young infants respond poorly to vaccines, but the basis of reduced immunity is controversial. We hypothesized that myeloid-derived suppressor cells (MDSC) that might be induced during gestation, w...

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Bibliographic Details
Main Author: Kidzeru, Elvis Banboye
Other Authors: Jaspan, Heather B
Format: Thesis
Language:English
Published: Division of Immunology 2016
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