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The crossed mesostriatal pathway and circling behaviour in rats
Bibliography: pages 326-345.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Department of Human Biology
2016
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| _version_ | 1867613199088484352 |
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| access_status_str | Open Access |
| author | Van Wageningen, Gerhard Derek |
| author2 | Douglas, Rodney J |
| author_browse | Douglas, Rodney J Van Wageningen, Gerhard Derek |
| author_facet | Douglas, Rodney J Van Wageningen, Gerhard Derek |
| author_sort | Van Wageningen, Gerhard Derek |
| collection | Thesis |
| description | Bibliography: pages 326-345. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/21152 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:20.328Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2016 |
| publishDateRange | 2016 |
| publishDateSort | 2016 |
| publisher | Department of Human Biology |
| publisherStr | Department of Human Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/21152 The crossed mesostriatal pathway and circling behaviour in rats Van Wageningen, Gerhard Derek Douglas, Rodney J Physiology Bibliography: pages 326-345. Rats with unilateral 6-OHDA lesions of the nigrostriatal (NS) projection display motor asymmetry in the form of rotational behaviour. The rotation is in the direction ipsilateral with respect to the lesioned side (Ungerstedt 1979). The nett ipsilateral rotations decrease with time, from 1 week to about a month. This decrease has been interpreted as recovery from the lesion-induced motor asymmetry (Glick and Cox 1978). Pritzel et al. (1983) have ascribed the recovery from motor asymmetry to increased activity of a crossed NS projection, which is spared by the ipsilateral lesion. The present study has defined the size and anatomical path of this crossed projection, and has examined its involvement in the behavioural recovery of rats from lesion-induced motor asymmetry. The anatomy of the crossed projection was investigated in male Long-Evans rats using retrograde HRP tract tracing from deposition sites in the striatum. 2016-08-05T10:54:29Z 2016-08-05T10:54:29Z 1987 Master Thesis Masters MSc http://hdl.handle.net/11427/21152 eng application/pdf Department of Human Biology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Physiology Van Wageningen, Gerhard Derek The crossed mesostriatal pathway and circling behaviour in rats |
| thesis_degree_str | Master's |
| title | The crossed mesostriatal pathway and circling behaviour in rats |
| title_full | The crossed mesostriatal pathway and circling behaviour in rats |
| title_fullStr | The crossed mesostriatal pathway and circling behaviour in rats |
| title_full_unstemmed | The crossed mesostriatal pathway and circling behaviour in rats |
| title_short | The crossed mesostriatal pathway and circling behaviour in rats |
| title_sort | crossed mesostriatal pathway and circling behaviour in rats |
| topic | Physiology |
| url | http://hdl.handle.net/11427/21152 |
| work_keys_str_mv | AT vanwageningengerhardderek thecrossedmesostriatalpathwayandcirclingbehaviourinrats AT vanwageningengerhardderek crossedmesostriatalpathwayandcirclingbehaviourinrats |