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Modelling of Residual Stresses of Blood Vessels

The diagnosis of vascular diseases can be achieved with a suitably determined circum­ferential stress at arterial walls. The stress distribution over arterial walls in blood vessels is affected by residual stresses and stresses due to blood pressure. However, residual stresses are still not reliably...

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Main Author: Omatuku, Emmanuel Ngongo
Format: Thesis
Language:English
Published: Department of Civil Engineering 2016
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access_status_str Open Access
author Omatuku, Emmanuel Ngongo
author_browse Omatuku, Emmanuel Ngongo
author_facet Omatuku, Emmanuel Ngongo
author_sort Omatuku, Emmanuel Ngongo
collection Thesis
description The diagnosis of vascular diseases can be achieved with a suitably determined circum­ferential stress at arterial walls. The stress distribution over arterial walls in blood vessels is affected by residual stresses and stresses due to blood pressure. However, residual stresses are still not reliably determined. For this reason, a suitable incorporation of these stresses is required in order to establish the wall stress as a reliable diagnostic indicator. Thus this study aims to model residual stresses by incorporating them into the wall stress distribution, and to investigate the effect that parameters defining the study constitutive model have on the stress distribution. The constitutive model makes use of the Cosserat fibre continuum in order to account for mechanics of arterial walls. It was developed for cardiac tissues by Skatulla et al. (2014), but it can also be used for a preliminary investigation on arterial tissues as these two types of tissues exhibit comparable mechanics. Residual stresses are incorporated by using three problem definitions, which are derived from the opening angle method, into a three dimensional two-layer artery con­sisting of the media and adventitia. The first problem incorporates residual stresses that are locked within individual load-free layers. The second problem continues the first problem by incorporating residual stresses acting at the interface surface between arterial layers, and then determine the artery wall stress distribution under blood pressure. The third problem determines the wall stress in the stress-free artery under blood pressure. On the other hand, the effect of parameters defining the constitutive model is investi­gated by varying the size of parameters in these problems. However, the second problem is not analysed in this study because it requires an analysis implementation that could not be achieved within the study timeline. Similarly, model parameters of problems are not calibrated to available experimental data. There­fore, this study only provides qualitative results. The investigation results on the incorporation of residual stresses into the stress distribution are found to be inconclusive as they provide contradictory results. The char­acteristic scaling parameters are found to influence the magnitude and gradient of the stress distribution. However, these results are not conclusive to clearly define the influ­ence. Thus it is recommended that further research be conducted in order to gain con­clusive results.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:33:31.121Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2016
publishDateRange 2016
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publisher Department of Civil Engineering
publisherStr Department of Civil Engineering
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source_str UCTD — University of Cape Town Open Access Repository
spelling oai:open.uct.ac.za:11427/21604 Modelling of Residual Stresses of Blood Vessels Omatuku, Emmanuel Ngongo The diagnosis of vascular diseases can be achieved with a suitably determined circum­ferential stress at arterial walls. The stress distribution over arterial walls in blood vessels is affected by residual stresses and stresses due to blood pressure. However, residual stresses are still not reliably determined. For this reason, a suitable incorporation of these stresses is required in order to establish the wall stress as a reliable diagnostic indicator. Thus this study aims to model residual stresses by incorporating them into the wall stress distribution, and to investigate the effect that parameters defining the study constitutive model have on the stress distribution. The constitutive model makes use of the Cosserat fibre continuum in order to account for mechanics of arterial walls. It was developed for cardiac tissues by Skatulla et al. (2014), but it can also be used for a preliminary investigation on arterial tissues as these two types of tissues exhibit comparable mechanics. Residual stresses are incorporated by using three problem definitions, which are derived from the opening angle method, into a three dimensional two-layer artery con­sisting of the media and adventitia. The first problem incorporates residual stresses that are locked within individual load-free layers. The second problem continues the first problem by incorporating residual stresses acting at the interface surface between arterial layers, and then determine the artery wall stress distribution under blood pressure. The third problem determines the wall stress in the stress-free artery under blood pressure. On the other hand, the effect of parameters defining the constitutive model is investi­gated by varying the size of parameters in these problems. However, the second problem is not analysed in this study because it requires an analysis implementation that could not be achieved within the study timeline. Similarly, model parameters of problems are not calibrated to available experimental data. There­fore, this study only provides qualitative results. The investigation results on the incorporation of residual stresses into the stress distribution are found to be inconclusive as they provide contradictory results. The char­acteristic scaling parameters are found to influence the magnitude and gradient of the stress distribution. However, these results are not conclusive to clearly define the influ­ence. Thus it is recommended that further research be conducted in order to gain con­clusive results. 2016-08-31T08:01:26Z 2016-08-31T08:01:26Z 2015 2016-08-31T07:57:09Z Thesis http://hdl.handle.net/11427/21604 eng application/pdf Department of Civil Engineering Faculty of Engineering and the Built Environment University of Cape Town
spellingShingle Omatuku, Emmanuel Ngongo
Modelling of Residual Stresses of Blood Vessels
title Modelling of Residual Stresses of Blood Vessels
title_full Modelling of Residual Stresses of Blood Vessels
title_fullStr Modelling of Residual Stresses of Blood Vessels
title_full_unstemmed Modelling of Residual Stresses of Blood Vessels
title_short Modelling of Residual Stresses of Blood Vessels
title_sort modelling of residual stresses of blood vessels
url http://hdl.handle.net/11427/21604
work_keys_str_mv AT omatukuemmanuelngongo modellingofresidualstressesofbloodvessels