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Insulin, added to nuclei, stimulates transcription of specific genes
Bibliography: pages 133-155.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Department of Molecular and Cell Biology
2016
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| _version_ | 1867613328262561792 |
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| access_status_str | Open Access |
| author | Stickells, Brenda Jane |
| author2 | Von Holt, Claus |
| author_browse | Stickells, Brenda Jane Von Holt, Claus |
| author_facet | Von Holt, Claus Stickells, Brenda Jane |
| author_sort | Stickells, Brenda Jane |
| collection | Thesis |
| description | Bibliography: pages 133-155. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/21984 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:23.309Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2016 |
| publishDateRange | 2016 |
| publishDateSort | 2016 |
| publisher | Department of Molecular and Cell Biology |
| publisherStr | Department of Molecular and Cell Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/21984 Insulin, added to nuclei, stimulates transcription of specific genes Stickells, Brenda Jane Von Holt, Claus Genetic transcription Insulin Bibliography: pages 133-155. Insulin regulates cellular gene expression and modulates specific mRNA levels in liver cells. As yet, the mechanism of this control is still unclear. The effects are initiated following the binding of insulin to the plasma membrane receptor. Although several mediators of the signal from the plasma membrane to the nucleus have been proposed, none has proved capable of eliciting all of the effects of insulin on gene expression. Therefore, the possibility that insulin itself may directly regulate transcription at the level of the nucleus, was investigated. 2016-09-28T19:05:29Z 2016-09-28T19:05:29Z 1990 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/21984 eng application/pdf Department of Molecular and Cell Biology Faculty of Science University of Cape Town |
| spellingShingle | Genetic transcription Insulin Stickells, Brenda Jane Insulin, added to nuclei, stimulates transcription of specific genes |
| thesis_degree_str | Doctoral |
| title | Insulin, added to nuclei, stimulates transcription of specific genes |
| title_full | Insulin, added to nuclei, stimulates transcription of specific genes |
| title_fullStr | Insulin, added to nuclei, stimulates transcription of specific genes |
| title_full_unstemmed | Insulin, added to nuclei, stimulates transcription of specific genes |
| title_short | Insulin, added to nuclei, stimulates transcription of specific genes |
| title_sort | insulin added to nuclei stimulates transcription of specific genes |
| topic | Genetic transcription Insulin |
| url | http://hdl.handle.net/11427/21984 |
| work_keys_str_mv | AT stickellsbrendajane insulinaddedtonucleistimulatestranscriptionofspecificgenes |