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A network analysis based proteomic and transcriptomic investigation into HIV-Tat induced neuronal dysfunction and the neuroprotective effect of lithium

HIV-associated neurocognitive disorders (HAND) affect up to 70% of HIV positive individuals and are the leading cause of dementia in patients under 40 years. Despite this, the molecular mechanisms involved in the onset of HAND are not well understood. Among a number of plausible etiological agents o...

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Bibliographic Details
Main Author: Ganief, Tariq Ahmad
Other Authors: Blackburn, Jonathan M
Format: Thesis
Language:English
Published: Division of Medical Biochemistry 2017
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