New methodology for the synthesis of chiral, non-racemic a-tertiary amine centres: application to the synthesis of the marine alkaloid lepadiformine

The development of new methodology for the synthesis of a chiral, non-racemic quaternary carbon bearing an α-nitrogen (an α-tertiary amine or ATA) continues to be an active area of modern research in current synthetic organic chemistry. As a privileged biological scaffold, ATAs are widespread amongs...

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