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Studies in cardiomyopathy: looking beyond the familiar
Background: Little is known about the mechanisms, clinical characteristics, natural history and outcomes of cardiomyopathy amongst Africans. Familial aggregation of cardiomyopathy has not been studied systematically in an African setting. Further, it is not clear whether the various phenotypic expre...
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| Format: | Thesis |
| Language: | English |
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Division of Cardiology
2017
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| _version_ | 1867613230268940288 |
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| access_status_str | Open Access |
| author | Ntusi, Ntobeko A B |
| author2 | Mayosi, Bongani M |
| author_browse | Mayosi, Bongani M Ntusi, Ntobeko A B |
| author_facet | Mayosi, Bongani M Ntusi, Ntobeko A B |
| author_sort | Ntusi, Ntobeko A B |
| collection | Thesis |
| description | Background: Little is known about the mechanisms, clinical characteristics, natural history and outcomes of cardiomyopathy amongst Africans. Familial aggregation of cardiomyopathy has not been studied systematically in an African setting. Further, it is not clear whether the various phenotypic expressions of cardiomyopathy represent disparate clinical entities, or whether they are merely different forms of the same disease manifested differently in different circumstances. Methods: Two cohorts of patients with cardiomyopathy were utilised for this study: (1) patients with cardiomyopathy seen at the specialist cardiomyopathy clinic at Groote Schuur Hospital, Cape Town between February 1, 1996 and December 31, 2009; and (2) a group of hypertrophic cardiomyopathy (HCM) patients and first degree relatives seen in a specialist cardiogenetic clinic at Tygerberg Hospital, who underwent cardiovascular magnetic resonance (CMR) imaging at Groote Schuur Hospital. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/22776 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:50.328Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Division of Cardiology |
| publisherStr | Division of Cardiology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/22776 Studies in cardiomyopathy: looking beyond the familiar Ntusi, Ntobeko A B Mayosi, Bongani M Cardiology Background: Little is known about the mechanisms, clinical characteristics, natural history and outcomes of cardiomyopathy amongst Africans. Familial aggregation of cardiomyopathy has not been studied systematically in an African setting. Further, it is not clear whether the various phenotypic expressions of cardiomyopathy represent disparate clinical entities, or whether they are merely different forms of the same disease manifested differently in different circumstances. Methods: Two cohorts of patients with cardiomyopathy were utilised for this study: (1) patients with cardiomyopathy seen at the specialist cardiomyopathy clinic at Groote Schuur Hospital, Cape Town between February 1, 1996 and December 31, 2009; and (2) a group of hypertrophic cardiomyopathy (HCM) patients and first degree relatives seen in a specialist cardiogenetic clinic at Tygerberg Hospital, who underwent cardiovascular magnetic resonance (CMR) imaging at Groote Schuur Hospital. 2017-01-18T07:22:07Z 2017-01-18T07:22:07Z 2016 Doctoral Thesis Doctoral MD http://hdl.handle.net/11427/22776 eng application/pdf Division of Cardiology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Cardiology Ntusi, Ntobeko A B Studies in cardiomyopathy: looking beyond the familiar |
| thesis_degree_str | Doctoral |
| title | Studies in cardiomyopathy: looking beyond the familiar |
| title_full | Studies in cardiomyopathy: looking beyond the familiar |
| title_fullStr | Studies in cardiomyopathy: looking beyond the familiar |
| title_full_unstemmed | Studies in cardiomyopathy: looking beyond the familiar |
| title_short | Studies in cardiomyopathy: looking beyond the familiar |
| title_sort | studies in cardiomyopathy looking beyond the familiar |
| topic | Cardiology |
| url | http://hdl.handle.net/11427/22776 |
| work_keys_str_mv | AT ntusintobekoab studiesincardiomyopathylookingbeyondthefamiliar |