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A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital
Objective: To document the demographics, the pattern of clinical and laboratory characteristics at the time of diagnoses for all the newly diagnosed diabetics younger than 14 years reviewed at the Diabetic clinic at the Red Cross War Memorial Children's Hospital (RCWMH) during 2005-2009. Method: A r...
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| Format: | Thesis |
| Language: | English |
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Department of Paediatrics and Child Health
2017
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| _version_ | 1867613150211211264 |
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| access_status_str | Open Access |
| author | Botes, Alida Maria |
| author2 | Carrihill, Michelle Margaret |
| author_browse | Botes, Alida Maria Carrihill, Michelle Margaret |
| author_facet | Carrihill, Michelle Margaret Botes, Alida Maria |
| author_sort | Botes, Alida Maria |
| collection | Thesis |
| description | Objective: To document the demographics, the pattern of clinical and laboratory characteristics at the time of diagnoses for all the newly diagnosed diabetics younger than 14 years reviewed at the Diabetic clinic at the Red Cross War Memorial Children's Hospital (RCWMH) during 2005-2009. Method: A retrospective folder review was done of all the newly diagnosed diabetics younger than 14 years old at the age of diagnosis. 225 patients were included for analysis. Patients were grouped according to age into a young group (1 month to < 5 years old), a middle group (5years - < 9 years) and an older group (9years - <14 years). Neonates were excluded as well as children who became diabetic secondary to another condition. Results: 58% of the patients were female and most of the patients were diagnosed with type 1 diabetes (96%). The median age at diagnosis was 8.5 years with a mean HbA1c of 11, 3%. 68% of the patients were in the normal weight category while 8, 4% of the patients were obese. 148 (65%) of the 225 patients presented in diabetic ketoacidosis (DKA). Only one of the patients classified with type 2 diabetes presented in DKA. 51 (22,67%) of the patients were less than 4 years old at the time of diagnosis. 53% of the Caucasian children were less than 4 years old at diagnosis while most of the children in the black and coloured group were diagnosed after 10 years of age. A seasonal variation was seen especially in the young age group with 66% presenting in autumn or winter months. Conclusions: Almost a quarter of diabetic children presented before the age of 4 years. A large proportion of patients presented in diabetic ketoacidosis which can be life threatening. Due to lack of information at diagnosis, this could be under reported significantly and calls for increase awareness amongst physicians and parents to recognise symptoms earlier. Prospective studies on childhood diabetes in South Africa are needed as well as a registry for childhood diabetes. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/22985 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:34.243Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Department of Paediatrics and Child Health |
| publisherStr | Department of Paediatrics and Child Health |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/22985 A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital Botes, Alida Maria Carrihill, Michelle Margaret Paediatrics Objective: To document the demographics, the pattern of clinical and laboratory characteristics at the time of diagnoses for all the newly diagnosed diabetics younger than 14 years reviewed at the Diabetic clinic at the Red Cross War Memorial Children's Hospital (RCWMH) during 2005-2009. Method: A retrospective folder review was done of all the newly diagnosed diabetics younger than 14 years old at the age of diagnosis. 225 patients were included for analysis. Patients were grouped according to age into a young group (1 month to < 5 years old), a middle group (5years - < 9 years) and an older group (9years - <14 years). Neonates were excluded as well as children who became diabetic secondary to another condition. Results: 58% of the patients were female and most of the patients were diagnosed with type 1 diabetes (96%). The median age at diagnosis was 8.5 years with a mean HbA1c of 11, 3%. 68% of the patients were in the normal weight category while 8, 4% of the patients were obese. 148 (65%) of the 225 patients presented in diabetic ketoacidosis (DKA). Only one of the patients classified with type 2 diabetes presented in DKA. 51 (22,67%) of the patients were less than 4 years old at the time of diagnosis. 53% of the Caucasian children were less than 4 years old at diagnosis while most of the children in the black and coloured group were diagnosed after 10 years of age. A seasonal variation was seen especially in the young age group with 66% presenting in autumn or winter months. Conclusions: Almost a quarter of diabetic children presented before the age of 4 years. A large proportion of patients presented in diabetic ketoacidosis which can be life threatening. Due to lack of information at diagnosis, this could be under reported significantly and calls for increase awareness amongst physicians and parents to recognise symptoms earlier. Prospective studies on childhood diabetes in South Africa are needed as well as a registry for childhood diabetes. 2017-01-24T09:12:01Z 2017-01-24T09:12:01Z 2016 Master Thesis Masters MMed http://hdl.handle.net/11427/22985 eng application/pdf Department of Paediatrics and Child Health Faculty of Health Sciences University of Cape Town |
| spellingShingle | Paediatrics Botes, Alida Maria A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital |
| thesis_degree_str | Master's |
| title | A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital |
| title_full | A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital |
| title_fullStr | A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital |
| title_full_unstemmed | A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital |
| title_short | A description of the characteristics at presentation of children diagnosed with Diabetes Mellitus from 2005-2009 at Red Cross War Memorial Children's Hospital |
| title_sort | description of the characteristics at presentation of children diagnosed with diabetes mellitus from 2005 2009 at red cross war memorial children s hospital |
| topic | Paediatrics |
| url | http://hdl.handle.net/11427/22985 |
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