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An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008
Background: Borderline ovarian tumours (BOT) are an intermediate form of neoplasia, between benign and malignant and have been classified as epithelial tumours of low malignant potential. These particular tumours affect a younger age group than their invasive counterparts with an overall survival of...
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| Format: | Thesis |
| Language: | English |
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Department of Obstetrics and Gynaecology
2017
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| _version_ | 1867613756592226304 |
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| access_status_str | Open Access |
| author | Hendricks, Aneeqah |
| author2 | Denny, Lynette |
| author_browse | Denny, Lynette Hendricks, Aneeqah |
| author_facet | Denny, Lynette Hendricks, Aneeqah |
| author_sort | Hendricks, Aneeqah |
| collection | Thesis |
| description | Background: Borderline ovarian tumours (BOT) are an intermediate form of neoplasia, between benign and malignant and have been classified as epithelial tumours of low malignant potential. These particular tumours affect a younger age group than their invasive counterparts with an overall survival of 90 - 100%. The present study aims to document the experience of a single centre on the management of women with borderline ovarian tumours (BOT). Methods: Two hundred and thirteen patients diagnosed and treated with BOT between 1984 and 2008 were identified through the Gynaecology Oncology database that has been in existence since 1984. Details of management, outcome and survival were retrieved and data were analysed descriptively and for survival. Results: The median age at diagnosis was 45 years old, with 34 % of patients > 40 years old. The incidence of serous BOT (SBOT) was 47.9% (102/213) and 49.3 % (105/213) were mucinous BOT (MBOT). Most of the patients were diagnosed in Stage I 83.6% (178/213), 6.1%( 13/213) were in stage II and 10.0% (22/213) were stage III. There were no patients in stage IV. At the end of the study period 73% (156/213) of the women were alive with no evidence of disease. Univariate analysis, indicated that the histological subtype of tumour, the type of surgery, the presence of residual disease, advanced stage disease, the presence of ascites were all statistically significant in affecting survival. Multivariate analysis, however, revealed that only the presence of residual disease was statistically significant as a prognostic predictor of poor outcome. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/25292 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:41:12.628Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Department of Obstetrics and Gynaecology |
| publisherStr | Department of Obstetrics and Gynaecology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/25292 An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 Hendricks, Aneeqah Denny, Lynette van Wijk, Leon Gynaecology Background: Borderline ovarian tumours (BOT) are an intermediate form of neoplasia, between benign and malignant and have been classified as epithelial tumours of low malignant potential. These particular tumours affect a younger age group than their invasive counterparts with an overall survival of 90 - 100%. The present study aims to document the experience of a single centre on the management of women with borderline ovarian tumours (BOT). Methods: Two hundred and thirteen patients diagnosed and treated with BOT between 1984 and 2008 were identified through the Gynaecology Oncology database that has been in existence since 1984. Details of management, outcome and survival were retrieved and data were analysed descriptively and for survival. Results: The median age at diagnosis was 45 years old, with 34 % of patients > 40 years old. The incidence of serous BOT (SBOT) was 47.9% (102/213) and 49.3 % (105/213) were mucinous BOT (MBOT). Most of the patients were diagnosed in Stage I 83.6% (178/213), 6.1%( 13/213) were in stage II and 10.0% (22/213) were stage III. There were no patients in stage IV. At the end of the study period 73% (156/213) of the women were alive with no evidence of disease. Univariate analysis, indicated that the histological subtype of tumour, the type of surgery, the presence of residual disease, advanced stage disease, the presence of ascites were all statistically significant in affecting survival. Multivariate analysis, however, revealed that only the presence of residual disease was statistically significant as a prognostic predictor of poor outcome. 2017-09-22T12:01:55Z 2017-09-22T12:01:55Z 2017 Master Thesis Masters MMed http://hdl.handle.net/11427/25292 eng application/pdf Department of Obstetrics and Gynaecology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Gynaecology Hendricks, Aneeqah An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 |
| thesis_degree_str | Master's |
| title | An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 |
| title_full | An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 |
| title_fullStr | An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 |
| title_full_unstemmed | An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 |
| title_short | An audit of the management of women with Borderline Ovarian Tumours treated at Groote Schuur Hospital between 1984-2008 |
| title_sort | audit of the management of women with borderline ovarian tumours treated at groote schuur hospital between 1984 2008 |
| topic | Gynaecology |
| url | http://hdl.handle.net/11427/25292 |
| work_keys_str_mv | AT hendricksaneeqah anauditofthemanagementofwomenwithborderlineovariantumourstreatedatgrooteschuurhospitalbetween19842008 AT hendricksaneeqah auditofthemanagementofwomenwithborderlineovariantumourstreatedatgrooteschuurhospitalbetween19842008 |