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Acute dichromate poisoning following the use of toxic purgatives
During the last ten years, several patients have presented to the Renal Unit of Groote Schuur Hospital with acute renal failure following the use of traditional (N'anga or Gqirha) medication. The history together with abnormal liver-function tests and renal failure was thought to be suggestive of a...
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| Format: | Thesis |
| Language: | English |
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Department of Medicine
2017
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| _version_ | 1867613208913641472 |
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| access_status_str | Open Access |
| author | Wood, Robin |
| author_browse | Wood, Robin |
| author_facet | Wood, Robin |
| author_sort | Wood, Robin |
| collection | Thesis |
| description | During the last ten years, several patients have presented to the Renal Unit of Groote Schuur Hospital with acute renal failure following the use of traditional (N'anga or Gqirha) medication. The history together with abnormal liver-function tests and renal failure was thought to be suggestive of a toxic aetiology. The specific toxin however remained unknown, until during the admission of one patient, a relative brought in the medication, analysis of which revealed a high concentration of potassium dichromate. Subsequently elevated levels of chromium were demonstrated by atomic absorption spectrometry in the blood and urine of this patient. Following this case there have been six further cases of acute renal failure resulting from use of dichromate containing traditional remedies. These remedies were obtained from a variety of sources including street-hawkers, herbal chemists, and traditional healers. Clinical and laboratory data relating to these seven patients will be presented. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/25577 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:29.432Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Department of Medicine |
| publisherStr | Department of Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/25577 Acute dichromate poisoning following the use of toxic purgatives Wood, Robin Cathartics - poisoning Kidney Failure, Acute - etiology Potassium Dichromate - poisoning During the last ten years, several patients have presented to the Renal Unit of Groote Schuur Hospital with acute renal failure following the use of traditional (N'anga or Gqirha) medication. The history together with abnormal liver-function tests and renal failure was thought to be suggestive of a toxic aetiology. The specific toxin however remained unknown, until during the admission of one patient, a relative brought in the medication, analysis of which revealed a high concentration of potassium dichromate. Subsequently elevated levels of chromium were demonstrated by atomic absorption spectrometry in the blood and urine of this patient. Following this case there have been six further cases of acute renal failure resulting from use of dichromate containing traditional remedies. These remedies were obtained from a variety of sources including street-hawkers, herbal chemists, and traditional healers. Clinical and laboratory data relating to these seven patients will be presented. 2017-10-11T10:54:52Z 2017-10-11T10:54:52Z 1990 2017-07-12T11:32:23Z Master Thesis Masters MMed http://hdl.handle.net/11427/25577 eng application/pdf Department of Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Cathartics - poisoning Kidney Failure, Acute - etiology Potassium Dichromate - poisoning Wood, Robin Acute dichromate poisoning following the use of toxic purgatives |
| thesis_degree_str | Master's |
| title | Acute dichromate poisoning following the use of toxic purgatives |
| title_full | Acute dichromate poisoning following the use of toxic purgatives |
| title_fullStr | Acute dichromate poisoning following the use of toxic purgatives |
| title_full_unstemmed | Acute dichromate poisoning following the use of toxic purgatives |
| title_short | Acute dichromate poisoning following the use of toxic purgatives |
| title_sort | acute dichromate poisoning following the use of toxic purgatives |
| topic | Cathartics - poisoning Kidney Failure, Acute - etiology Potassium Dichromate - poisoning |
| url | http://hdl.handle.net/11427/25577 |
| work_keys_str_mv | AT woodrobin acutedichromatepoisoningfollowingtheuseoftoxicpurgatives |