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Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry
AIMS OF THE STUDY: 1. To perform a retrospective, epidemiological analysis of cases of reactive lymphadenopathy and atypical reactive lymphoid hyperplasia (ARLH) received in the Department of Anatomical Pathology, UCT and GSH, over a 5 year period, in order to determine the number of cases of ARLH,...
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| Format: | Thesis |
| Language: | English English |
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Division of Anatomical Pathology
2017
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| _version_ | 1867613233992433664 |
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| access_status_str | Open Access |
| author | Eedes, Christopher Robert Eedes, Christopher Robert |
| author2 | Close, Pauline |
| author_browse | Close, Pauline Eedes, Christopher Robert |
| author_facet | Close, Pauline Eedes, Christopher Robert Eedes, Christopher Robert |
| author_sort | Eedes, Christopher Robert |
| collection | Thesis |
| description | AIMS OF THE STUDY: 1. To perform a retrospective, epidemiological analysis of cases of reactive lymphadenopathy and atypical reactive lymphoid hyperplasia (ARLH) received in the Department of Anatomical Pathology, UCT and GSH, over a 5 year period, in order to determine the number of cases of ARLH, and the frequency of the various subtypes of reactive lymphoid. hyperplasia, so as to provide base-line information for further studies. 2. To set up IN SITU HYBRIDIZATION (ISH) for detection of Epstein-Barr virus (EBV)-encoded RNA's (EBERs) in latently infected cells in selected cases, to determine if virus is present in ARLH. 3. To perform immunohistochemical analysis for the detection of EBY-derived latent membrane protein (LMP) in those cases subjected to ISH. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/25581 |
| institution | University of Cape Town (South Africa) |
| language | eng eng |
| last_indexed | 2026-06-10T12:32:52.713Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Division of Anatomical Pathology |
| publisherStr | Division of Anatomical Pathology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/25581 Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry Eedes, Christopher Robert Eedes, Christopher Robert Close, Pauline Herpesvirus 4, Human - chemistry Hyperplasia - etiology Hyperplasia - pathology Herpesvirus 4, Human - chemistry~Hyperplasia - etiology~Hyperplasia - pathology AIMS OF THE STUDY: 1. To perform a retrospective, epidemiological analysis of cases of reactive lymphadenopathy and atypical reactive lymphoid hyperplasia (ARLH) received in the Department of Anatomical Pathology, UCT and GSH, over a 5 year period, in order to determine the number of cases of ARLH, and the frequency of the various subtypes of reactive lymphoid. hyperplasia, so as to provide base-line information for further studies. 2. To set up IN SITU HYBRIDIZATION (ISH) for detection of Epstein-Barr virus (EBV)-encoded RNA's (EBERs) in latently infected cells in selected cases, to determine if virus is present in ARLH. 3. To perform immunohistochemical analysis for the detection of EBY-derived latent membrane protein (LMP) in those cases subjected to ISH. 2017-10-11T10:57:46Z 2017-10-11T10:57:46Z 1994 2017-07-12T11:33:06Z Master Thesis Masters MMed http://hdl.handle.net/11427/25581 eng eng application/pdf Division of Anatomical Pathology Faculty of Health Sciences University of Cape Town University of Cape Town |
| spellingShingle | Herpesvirus 4, Human - chemistry Hyperplasia - etiology Hyperplasia - pathology Herpesvirus 4, Human - chemistry~Hyperplasia - etiology~Hyperplasia - pathology Eedes, Christopher Robert Eedes, Christopher Robert Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry |
| thesis_degree_str | Master's |
| title | Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry |
| title_full | Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry |
| title_fullStr | Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry |
| title_full_unstemmed | Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry |
| title_short | Atypical reactive lymphoid hyperplasia : a 5 year study with analysis of 10 cases for latent Epstein-Barr virus infection by in situ hybridization and immunohistochemistry |
| title_sort | atypical reactive lymphoid hyperplasia a 5 year study with analysis of 10 cases for latent epstein barr virus infection by in situ hybridization and immunohistochemistry |
| topic | Herpesvirus 4, Human - chemistry Hyperplasia - etiology Hyperplasia - pathology Herpesvirus 4, Human - chemistry~Hyperplasia - etiology~Hyperplasia - pathology |
| url | http://hdl.handle.net/11427/25581 |
| work_keys_str_mv | AT eedeschristopherrobert atypicalreactivelymphoidhyperplasiaa5yearstudywithanalysisof10casesforlatentepsteinbarrvirusinfectionbyinsituhybridizationandimmunohistochemistry AT eedeschristopherrobert atypicalreactivelymphoidhyperplasiaa5yearstudywithanalysisof10casesforlatentepsteinbarrvirusinfectionbyinsituhybridizationandimmunohistochemistry |