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Integrons and integron-related antibiotic resistance in acinetobacter
Acinetobacter baumannii is responsible for an increasing number of nosocomial infections in patients receiving intensive care and comprehensive antibiotic resistance of these organisms hampers treatment of infections due to A.baumannii. The molecular basis of antibiotic resistance in A.baumannii has...
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| Format: | Thesis |
| Language: | English |
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Division of Medical Microbiology
2017
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| _version_ | 1867613233994530816 |
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| access_status_str | Open Access |
| author | Thomas, Robin |
| author2 | Elisha, B Gay |
| author_browse | Elisha, B Gay Thomas, Robin |
| author_facet | Elisha, B Gay Thomas, Robin |
| author_sort | Thomas, Robin |
| collection | Thesis |
| description | Acinetobacter baumannii is responsible for an increasing number of nosocomial infections in patients receiving intensive care and comprehensive antibiotic resistance of these organisms hampers treatment of infections due to A.baumannii. The molecular basis of antibiotic resistance in A.baumannii has not been extensively investigated. A few studies have demonstrated the role of plasmids and transposons in resistance in this organism, but there is little data on the role of integrons and integron-associated antibiotic resistance. This study was undertaken to determine the incidence of integrons in clinical isolates of Acinetobacter from Groote Schuur Hospital (GSH), Cape Town and Universitas Hospital (UH), Bloemfontein, and to characterise the resistance genes carried in the variable regions of these integrons. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/25633 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:52.713Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Division of Medical Microbiology |
| publisherStr | Division of Medical Microbiology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/25633 Integrons and integron-related antibiotic resistance in acinetobacter Thomas, Robin Elisha, B Gay Medical Microbiology Acinetobacter baumannii is responsible for an increasing number of nosocomial infections in patients receiving intensive care and comprehensive antibiotic resistance of these organisms hampers treatment of infections due to A.baumannii. The molecular basis of antibiotic resistance in A.baumannii has not been extensively investigated. A few studies have demonstrated the role of plasmids and transposons in resistance in this organism, but there is little data on the role of integrons and integron-associated antibiotic resistance. This study was undertaken to determine the incidence of integrons in clinical isolates of Acinetobacter from Groote Schuur Hospital (GSH), Cape Town and Universitas Hospital (UH), Bloemfontein, and to characterise the resistance genes carried in the variable regions of these integrons. 2017-10-12T08:42:59Z 2017-10-12T08:42:59Z 1999 2017-07-13T10:40:42Z Master Thesis Masters MSc (Med) http://hdl.handle.net/11427/25633 eng application/pdf Division of Medical Microbiology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medical Microbiology Thomas, Robin Integrons and integron-related antibiotic resistance in acinetobacter |
| thesis_degree_str | Master's |
| title | Integrons and integron-related antibiotic resistance in acinetobacter |
| title_full | Integrons and integron-related antibiotic resistance in acinetobacter |
| title_fullStr | Integrons and integron-related antibiotic resistance in acinetobacter |
| title_full_unstemmed | Integrons and integron-related antibiotic resistance in acinetobacter |
| title_short | Integrons and integron-related antibiotic resistance in acinetobacter |
| title_sort | integrons and integron related antibiotic resistance in acinetobacter |
| topic | Medical Microbiology |
| url | http://hdl.handle.net/11427/25633 |
| work_keys_str_mv | AT thomasrobin integronsandintegronrelatedantibioticresistanceinacinetobacter |