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The diagnosis of primary pulmonary hypertension (PPH) and prediction of its course, whether treated or untreated, presents several problems. These are of particular relevance when selection of patients for, and timing of heart-lung transplantation is being considered. I performed a retrospective stu...
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| Format: | Thesis |
| Language: | English |
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Division of Pulmonology
2017
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| _version_ | 1867614181109268480 |
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| access_status_str | Open Access |
| author | Chapman, P J |
| author2 | Benatar, Solomon R |
| author_browse | Benatar, Solomon R Chapman, P J |
| author_facet | Benatar, Solomon R Chapman, P J |
| author_sort | Chapman, P J |
| collection | Thesis |
| description | The diagnosis of primary pulmonary hypertension (PPH) and prediction of its course, whether treated or untreated, presents several problems. These are of particular relevance when selection of patients for, and timing of heart-lung transplantation is being considered. I performed a retrospective study on patients with PPH and chronic large vessel thromboembolic pulmonary hypertension (TPH) seen at Groote Schuur Hospital between 1957 and 1985 in an attempt to: 1. Establish the diagnostic and prognostic value of clinical features, lung function tests, cardiac catheterisation, isotope lung scans and, in the PPH group, response to therapy; 2. Review our experience of the effects of treatment with vasodilators and oral anticoagulants, and the results of heart and lung transplantation in the PPH group; 3. Attempt to identify features which could be used to predict prognosis in PPH; and thereby 4. Define criteria for selecting PPH patients whose prognosis could be improved by heart-lung transplantation. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/25726 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:47:57.480Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2017 |
| publishDateRange | 2017 |
| publishDateSort | 2017 |
| publisher | Division of Pulmonology |
| publisherStr | Division of Pulmonology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/25726 Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension Chapman, P J Benatar, Solomon R Bateman, Eric D Pulmonary hypertension Pulmonology The diagnosis of primary pulmonary hypertension (PPH) and prediction of its course, whether treated or untreated, presents several problems. These are of particular relevance when selection of patients for, and timing of heart-lung transplantation is being considered. I performed a retrospective study on patients with PPH and chronic large vessel thromboembolic pulmonary hypertension (TPH) seen at Groote Schuur Hospital between 1957 and 1985 in an attempt to: 1. Establish the diagnostic and prognostic value of clinical features, lung function tests, cardiac catheterisation, isotope lung scans and, in the PPH group, response to therapy; 2. Review our experience of the effects of treatment with vasodilators and oral anticoagulants, and the results of heart and lung transplantation in the PPH group; 3. Attempt to identify features which could be used to predict prognosis in PPH; and thereby 4. Define criteria for selecting PPH patients whose prognosis could be improved by heart-lung transplantation. 2017-10-23T06:37:59Z 2017-10-23T06:37:59Z 1987 2017-07-20T13:03:33Z Master Thesis Masters MMed http://hdl.handle.net/11427/25726 eng application/pdf Division of Pulmonology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Pulmonary hypertension Pulmonology Chapman, P J Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension |
| thesis_degree_str | Master's |
| title | Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension |
| title_full | Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension |
| title_fullStr | Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension |
| title_full_unstemmed | Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension |
| title_short | Diagnostic, prognostic and therapeutic considerations in primary pulmonary hypertension |
| title_sort | diagnostic prognostic and therapeutic considerations in primary pulmonary hypertension |
| topic | Pulmonary hypertension Pulmonology |
| url | http://hdl.handle.net/11427/25726 |
| work_keys_str_mv | AT chapmanpj diagnosticprognosticandtherapeuticconsiderationsinprimarypulmonaryhypertension |