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An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs
Bibliography : leaves 84-104.
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Division of Chemical Pathology
2014
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| _version_ | 1867613246920327169 |
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| access_status_str | Open Access |
| author | Henshall-Howard, Marie-Paule Alix Emilie |
| author2 | Davidson, James |
| author_browse | Davidson, James Henshall-Howard, Marie-Paule Alix Emilie |
| author_facet | Davidson, James Henshall-Howard, Marie-Paule Alix Emilie |
| author_sort | Henshall-Howard, Marie-Paule Alix Emilie |
| collection | Thesis |
| description | Bibliography : leaves 84-104. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/2692 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:33:05.164Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Chemical Pathology |
| publisherStr | Division of Chemical Pathology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/2692 An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs Henshall-Howard, Marie-Paule Alix Emilie Davidson, James Chemical Pathology Bibliography : leaves 84-104. Three GnRH receptors with the mutations N102A, N102D and N102K, which were derived from the human GnRH receptor by site directed mutagenesis, were expressed in COS-1 cells. The effects of these mutations on the potency of seven C-terminally modified GnRH agonist analogs for the stimulation of IP production were determined. 2014-07-28T08:13:58Z 2014-07-28T08:13:58Z 2000 Master Thesis Masters MSc http://hdl.handle.net/11427/2692 eng application/pdf Division of Chemical Pathology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Chemical Pathology Henshall-Howard, Marie-Paule Alix Emilie An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs |
| thesis_degree_str | Master's |
| title | An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs |
| title_full | An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs |
| title_fullStr | An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs |
| title_full_unstemmed | An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs |
| title_short | An investigation of the role of N102 of the GnRH receptor in determining the potency of C-terminally modified agonist analogs |
| title_sort | investigation of the role of n102 of the gnrh receptor in determining the potency of c terminally modified agonist analogs |
| topic | Chemical Pathology |
| url | http://hdl.handle.net/11427/2692 |
| work_keys_str_mv | AT henshallhowardmariepaulealixemilie aninvestigationoftheroleofn102ofthegnrhreceptorindeterminingthepotencyofcterminallymodifiedagonistanalogs AT henshallhowardmariepaulealixemilie investigationoftheroleofn102ofthegnrhreceptorindeterminingthepotencyofcterminallymodifiedagonistanalogs |