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A study to determine the efficacy of A 0,2 μm air venting final in-line intravenous filter in reducing the complications of intravenous therapy
Includes bibliographies.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Clinical Pharmacology
2018
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| _version_ | 1867613321260171264 |
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| access_status_str | Open Access |
| author | Stanford, J A |
| author2 | Folb, Peter I |
| author_browse | Folb, Peter I Stanford, J A |
| author_facet | Folb, Peter I Stanford, J A |
| author_sort | Stanford, J A |
| collection | Thesis |
| description | Includes bibliographies. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/26997 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:14.045Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| publisher | Division of Clinical Pharmacology |
| publisherStr | Division of Clinical Pharmacology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/26997 A study to determine the efficacy of A 0,2 μm air venting final in-line intravenous filter in reducing the complications of intravenous therapy Stanford, J A Folb, Peter I Forder, A A Infusions, Parenteral - Instrumentation Phlebitis Pharmacology Includes bibliographies. The effect of a 0,2 μm air venting in-line filter on the incidence of post-infusion phlebitis was studied in a prospective, controlled, observer-blind investigation of 132 infusions. The filters were changed daily and the infusions were allowed to continue until no longer required, or until there was a reason for discontinuation. Microbiological evaluation of filters, skin at the site of cannulation immediately prior to removal of cannulae, and cannula tips was performed. Particle size analyses of the commonly used intravenous infusion fluids and medicines was also carried out. The incidence of phlebitis was significantly reduced by the inclusion of the filter in-line. The efficacy of the filter in reducing phlebitis was most pronounced when intravenous antimicrobial agents, especially the cephalosporins, were administered. Micro-organisms were isolated from 13% (28/209) of filters which originated from 31% (16/32) of infusions with filters in-line. A relationship could not be established between the number of filters used per infusion or the number of intravenous additives to the infusion system. Phlebitis was not associated with microbial contamination of cannula tips. Medicines for intravenous administration, especially the powders to be reconstituted prior to administration, were heavily contaminated with particulate matter prior to filtration. 2018-01-25T14:00:20Z 2018-01-25T14:00:20Z 1984 Master Thesis Masters MSc (Med) http://hdl.handle.net/11427/26997 eng application/pdf Division of Clinical Pharmacology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Infusions, Parenteral - Instrumentation Phlebitis Pharmacology Stanford, J A A study to determine the efficacy of A 0,2 μm air venting final in-line intravenous filter in reducing the complications of intravenous therapy |
| thesis_degree_str | Master's |
| title | A study to determine the efficacy of A 0,2 μm air venting final in-line intravenous filter in reducing the complications of intravenous therapy |
| title_full | A study to determine the efficacy of A 0,2 μm air venting final in-line intravenous filter in reducing the complications of intravenous therapy |
| title_fullStr | A study to determine the efficacy of A 0,2 μm air venting final in-line intravenous filter in reducing the complications of intravenous therapy |
| title_full_unstemmed | A study to determine the efficacy of A 0,2 μm air venting final in-line intravenous filter in reducing the complications of intravenous therapy |
| title_short | A study to determine the efficacy of A 0,2 μm air venting final in-line intravenous filter in reducing the complications of intravenous therapy |
| title_sort | study to determine the efficacy of a 0 2 μm air venting final in line intravenous filter in reducing the complications of intravenous therapy |
| topic | Infusions, Parenteral - Instrumentation Phlebitis Pharmacology |
| url | http://hdl.handle.net/11427/26997 |
| work_keys_str_mv | AT stanfordja astudytodeterminetheefficacyofa02mmairventingfinalinlineintravenousfilterinreducingthecomplicationsofintravenoustherapy AT stanfordja studytodeterminetheefficacyofa02mmairventingfinalinlineintravenousfilterinreducingthecomplicationsofintravenoustherapy |