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Whole Blood Mitochondrial DNA Depletion in Human Immunodeficiency Virus-Infected Children
Background: Nucleoside reverse transcriptase inhibitors (NRTIs) interfere with mitochondrial DNA polymerase gamma causing significant toxic effects, including fatal lactic acidosis. Little is known about mitochondrial DNA (mtDNA) in human immunodeficiency virus (HIV) infected children who face a lif...
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| Format: | Thesis |
| Language: | English |
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Division of Chemical Pathology
2014
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