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The impact of HIV-1 subtype C Envelope N-glycosylation on DC-SIGN meditated modulation of DC function to facilitate transmission or enhance viral pathogenesis

N-glycosylation plays an important role in Envelope (Env) function and may be involved in the modulation of the immune response to HIV-1 infection. In this study, we hypothesized that Env N-glycosylation may affect viral pathogenesis by influencing Env structure and function. Furthermore, we also po...

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Bibliographic Details
Main Author: Lumngwena, Evelyn Ngwa
Other Authors: Woodman, Zenda
Format: Thesis
Language:English
Published: Department of Molecular and Cell Biology 2018
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