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The pharmacological modification of reperfusion injury with particular reference to calcium fluxes in the isolated rat heart

Myocardial reperfusion injury is thought to be caused by reperfusion induced i) cytosolic Ca²⁺ overload and/or, ii) the formation of oxygen derived freeradicals. At the start of this study, data implicating cytosolic Ca²⁺ overload in the genesis of reversible reperfusion injury were inconclusive. Al...

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Bibliographic Details
Main Author: Du Toit, Eugene Francois
Other Authors: Opie, Lionel H
Format: Thesis
Language:English
Published: Division of Cardiology 2018
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