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The value of routine histological examination of curettings in all first and second trimester abortions

A prospective study was carried out to assess whether, in first and second trimester abortions, the clinical diagnosis together with the macroscopic appearance of the curettings was an accurate guide to the correct diagnosis, and whether routine histological examination of all curettings was therefo...

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Main Author: Stewart, Chantal Juanita Michelle
Other Authors: Anthony, John
Format: Thesis
Language:English
Published: Department of Obstetrics and Gynaecology 2018
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access_status_str Open Access
author Stewart, Chantal Juanita Michelle
author2 Anthony, John
author_browse Anthony, John
Stewart, Chantal Juanita Michelle
author_facet Anthony, John
Stewart, Chantal Juanita Michelle
author_sort Stewart, Chantal Juanita Michelle
collection Thesis
description A prospective study was carried out to assess whether, in first and second trimester abortions, the clinical diagnosis together with the macroscopic appearance of the curettings was an accurate guide to the correct diagnosis, and whether routine histological examination of all curettings was therefore necessary. The study included 1 464 consecutive patients presenting to the Gynaecology Department at Groote Schuur Hospital, Cape Town with clinically diagnosed abortions during the period 1st February 1988 to 31st December 1988. The correlation between the macroscopic appearance and histological examination compatible with the diagnosis of abortion was found to be 86%. Where the diagnosis was in doubt this correlation was lower. The sensitivity of using the macroscopic appearance as a screening test for the diagnosis of abortion was 96%, with a positive predictive value of 91%. The kappa statistic of agreement between macroscopic appearance and histology was 0,26. The incidence of gestational trophoblastic disease in this series was 0.06%. The diagnosis of ectopic pregnancy was not aided by the use of routine histology.
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institution University of Cape Town (South Africa)
language eng
last_indexed 2026-06-10T12:33:57.504Z
license_str Not specified — see source repository
provenance_str_mv Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository
publishDate 2018
publishDateRange 2018
publishDateSort 2018
publisher Department of Obstetrics and Gynaecology
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spelling oai:open.uct.ac.za:11427/27135 The value of routine histological examination of curettings in all first and second trimester abortions Stewart, Chantal Juanita Michelle Anthony, John Obstetrics and Gynaecology Curettage - methods Abortion - diagnosis Abortion - pathology A prospective study was carried out to assess whether, in first and second trimester abortions, the clinical diagnosis together with the macroscopic appearance of the curettings was an accurate guide to the correct diagnosis, and whether routine histological examination of all curettings was therefore necessary. The study included 1 464 consecutive patients presenting to the Gynaecology Department at Groote Schuur Hospital, Cape Town with clinically diagnosed abortions during the period 1st February 1988 to 31st December 1988. The correlation between the macroscopic appearance and histological examination compatible with the diagnosis of abortion was found to be 86%. Where the diagnosis was in doubt this correlation was lower. The sensitivity of using the macroscopic appearance as a screening test for the diagnosis of abortion was 96%, with a positive predictive value of 91%. The kappa statistic of agreement between macroscopic appearance and histology was 0,26. The incidence of gestational trophoblastic disease in this series was 0.06%. The diagnosis of ectopic pregnancy was not aided by the use of routine histology. 2018-01-30T13:59:52Z 2018-01-30T13:59:52Z 1992 Master Thesis Masters MMed http://hdl.handle.net/11427/27135 eng application/pdf Department of Obstetrics and Gynaecology Faculty of Health Sciences University of Cape Town
spellingShingle Obstetrics and Gynaecology
Curettage - methods
Abortion - diagnosis
Abortion - pathology
Stewart, Chantal Juanita Michelle
The value of routine histological examination of curettings in all first and second trimester abortions
thesis_degree_str Master's
title The value of routine histological examination of curettings in all first and second trimester abortions
title_full The value of routine histological examination of curettings in all first and second trimester abortions
title_fullStr The value of routine histological examination of curettings in all first and second trimester abortions
title_full_unstemmed The value of routine histological examination of curettings in all first and second trimester abortions
title_short The value of routine histological examination of curettings in all first and second trimester abortions
title_sort value of routine histological examination of curettings in all first and second trimester abortions
topic Obstetrics and Gynaecology
Curettage - methods
Abortion - diagnosis
Abortion - pathology
url http://hdl.handle.net/11427/27135
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