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Photoaffinity labeling the nucleotide sites of the sarcoplasmic reticulum Ca²⁺-ATPase

We have synthesized a new class of photoaffinity analogs, 2',3'-O-(2,4,6-trinitrophenyl)-8-azido-ATP, -ADP and -AMP (TNP- 8N₃ATP, -ADP and -AMP), and their radiolabeled derivatives, and characterized their interaction with the sarcoplasmic reticulum Ca²⁺-ATPase. The TNP-8N₃-nucleotides were synthesi...

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Bibliographic Details
Main Author: Seebregts, Christopher J
Other Authors: McIntosh, David B
Format: Thesis
Language:English
Published: Division of Chemical Pathology 2018
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