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Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration
Nifedipine, in a 5mg sublingual acute administration, causes a significant fall in the systolic, diastolic and mean arterial pressure in a mixed group of pregnant hypertensives. A concurrent, significant rise in the pulse rate was seen. The utero-placental blood flow index, which is a measure of ute...
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| Format: | Thesis |
| Language: | English |
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Department of Obstetrics and Gynaecology
2018
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| _version_ | 1867613312572719104 |
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| access_status_str | Open Access |
| author | Lindow, S W |
| author2 | Davey, D A |
| author_browse | Davey, D A Lindow, S W |
| author_facet | Davey, D A Lindow, S W |
| author_sort | Lindow, S W |
| collection | Thesis |
| description | Nifedipine, in a 5mg sublingual acute administration, causes a significant fall in the systolic, diastolic and mean arterial pressure in a mixed group of pregnant hypertensives. A concurrent, significant rise in the pulse rate was seen. The utero-placental blood flow index, which is a measure of utero-placental blood flow, was not significantly reduced following the administration of Nifedipine or a placebo. The utero-placental blood flow index was found to be a consistent measure of utero-placental blood flow in resting patients. In the absence of serious side-effects it can be concluded that Nifedipine is a safe therapy in the acute treatment of hypertensive states in pregnancy. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/27206 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:08.683Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2018 |
| publishDateRange | 2018 |
| publishDateSort | 2018 |
| publisher | Department of Obstetrics and Gynaecology |
| publisherStr | Department of Obstetrics and Gynaecology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/27206 Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration Lindow, S W Davey, D A Maternal-fetal exchange Placenta Nifedipine Nifedipine, in a 5mg sublingual acute administration, causes a significant fall in the systolic, diastolic and mean arterial pressure in a mixed group of pregnant hypertensives. A concurrent, significant rise in the pulse rate was seen. The utero-placental blood flow index, which is a measure of utero-placental blood flow, was not significantly reduced following the administration of Nifedipine or a placebo. The utero-placental blood flow index was found to be a consistent measure of utero-placental blood flow in resting patients. In the absence of serious side-effects it can be concluded that Nifedipine is a safe therapy in the acute treatment of hypertensive states in pregnancy. 2018-02-01T13:32:06Z 2018-02-01T13:32:06Z 1987 Master Thesis Masters MMed http://hdl.handle.net/11427/27206 eng application/pdf Department of Obstetrics and Gynaecology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Maternal-fetal exchange Placenta Nifedipine Lindow, S W Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration |
| thesis_degree_str | Master's |
| title | Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration |
| title_full | Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration |
| title_fullStr | Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration |
| title_full_unstemmed | Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration |
| title_short | Utero-placental blood flow in hypertensive pregnancy and the effect of nifedipine administration |
| title_sort | utero placental blood flow in hypertensive pregnancy and the effect of nifedipine administration |
| topic | Maternal-fetal exchange Placenta Nifedipine |
| url | http://hdl.handle.net/11427/27206 |
| work_keys_str_mv | AT lindowsw uteroplacentalbloodflowinhypertensivepregnancyandtheeffectofnifedipineadministration |