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The interaction of three local anaesthetic agents with hepatic microsomal cytochrome P-450

The effect of inducing agents of cytochrome P-450 on the binding and metabolism of three local anaesthetic agents: lidocaine, mepivacaine and bupivacaine has been investigated. All three local anaesthetic agents bound to the type I binding site of cytochrome P-450, which is characteristic of substra...

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Bibliographic Details
Main Author: Van den Honert, Leonard Howard
Other Authors: Ivanetich, Kathryn M
Format: Thesis
Language:English
Published: Division of Medical Biochemistry and Structural Biology 2018
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