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The association of the AVPR2 gene with serum sodium and water imbalances during an Ironman Triathlon
Includes bibliographical references (p. 120-138).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
MRC/UCT RU for Exercise and Sport Medicine
2014
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| _version_ | 1867613230289911808 |
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| access_status_str | Open Access |
| author | Ah Kun, Maresa |
| author2 | Collins, Malcolm |
| author_browse | Ah Kun, Maresa Collins, Malcolm |
| author_facet | Collins, Malcolm Ah Kun, Maresa |
| author_sort | Ah Kun, Maresa |
| collection | Thesis |
| description | Includes bibliographical references (p. 120-138). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/2774 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:50.328Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | MRC/UCT RU for Exercise and Sport Medicine |
| publisherStr | MRC/UCT RU for Exercise and Sport Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/2774 The association of the AVPR2 gene with serum sodium and water imbalances during an Ironman Triathlon Ah Kun, Maresa Collins, Malcolm Sports Medicine Includes bibliographical references (p. 120-138). It is well documented that participation in ultra-endurance events such as the Ironman Triathlon, can be associated with the development of post-race water and sodium imbalances in athletes. Variants within genes that encode for proteins that regulate thirst have been shown to be associated with weight changes during participation in an Ironman Triathlon. Recent evidence of mutations within the arginine vasopressin 2 receptor (AVPR2) gene, which encodes a constitutively active receptor in the collecting tubules of the kidney, resulted in increased water reabsorption and hyponatraemia in two unrelated male infants. This suggests that serum imbalances and hydration status in individuals participating in an endurance event may also be, in part, controlled by variants withink the AVPR2 gene. The aim of this study was to investigate whether polymorphisms within the AVPR2 gene are associated with exercise-associated serum sodium and/or water imbalances in triathletes who particpated in the 2006 South African Ironman Triathlon. 2014-07-28T08:24:03Z 2014-07-28T08:24:03Z 2007 Master Thesis Masters MPhil http://hdl.handle.net/11427/2774 eng application/pdf MRC/UCT RU for Exercise and Sport Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Sports Medicine Ah Kun, Maresa The association of the AVPR2 gene with serum sodium and water imbalances during an Ironman Triathlon |
| thesis_degree_str | Master's |
| title | The association of the AVPR2 gene with serum sodium and water imbalances during an Ironman Triathlon |
| title_full | The association of the AVPR2 gene with serum sodium and water imbalances during an Ironman Triathlon |
| title_fullStr | The association of the AVPR2 gene with serum sodium and water imbalances during an Ironman Triathlon |
| title_full_unstemmed | The association of the AVPR2 gene with serum sodium and water imbalances during an Ironman Triathlon |
| title_short | The association of the AVPR2 gene with serum sodium and water imbalances during an Ironman Triathlon |
| title_sort | association of the avpr2 gene with serum sodium and water imbalances during an ironman triathlon |
| topic | Sports Medicine |
| url | http://hdl.handle.net/11427/2774 |
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