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Prevalence of anxiety disorders among people living with HIV (PLWHIV) and experiencing neuropathic pain who attend clinics in Nkomazi Sub-District
Background: Clinical and research experience indicates that a high HIV prevalence setting will have a high occurrence of conditions that are associated with HIV. These conditions are not always infectious in nature. General physiological pain, neuropathic pain (NeuP) and anxiety disorders are condit...
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| Format: | Thesis |
| Language: | English |
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Department of Public Health and Family Medicine
2019
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| _version_ | 1867613335859494912 |
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| access_status_str | Open Access |
| author | Ochan, Walter O |
| author2 | Gwyther, Liz |
| author_browse | Gwyther, Liz Ochan, Walter O |
| author_facet | Gwyther, Liz Ochan, Walter O |
| author_sort | Ochan, Walter O |
| collection | Thesis |
| description | Background: Clinical and research experience indicates that a high HIV prevalence setting will have a high occurrence of conditions that are associated with HIV. These conditions are not always infectious in nature. General physiological pain, neuropathic pain (NeuP) and anxiety disorders are conditions that have a high prevalence in people living with HIV (PLWHIV). There is, however, a literature gap on the prevalence of these conditions in Nkomazi Sub-district in South Africa’s Mpumalanga Province. This study therefore aimed to serve as a baseline study for the determination of the prevalence of anxiety disorders and neuropathic pain amongst PLWHIV who attended Highly Active Antiretroviral Therapy (HAART) clinics in Nkomazi Sub-district.
Aim of the study: To determine the prevalence of anxiety disorders among PLWHIV with neuropathic pain who attended HAART clinics in Nkomazi sub-district. Objectives of the study: 1) To determine the prevalence of Neuropathic Pain among patients attending HIV clinics in Nkomazi Health District; 2) To determine the prevalence of Anxiety disorders among PLWHIV experiencing neuropathic pain who attended HIV clinics in Nkomazi sub-district. 3) To determine the Types of Anxiety Disorder among Nkomazi PLWHIV with NeuP who have one, or more anxiety disorders.
Methods: The objectives were achieved through a cross-sectional study using an interviewer administered questionnaire. Three out of 34 facilities were sampled for the study and participants were recruited and interviewed for a month in April 2013. A total of 508 participants were recruited. The questionnaire was adapted from the Structured Clinical Interview DSM IV Axis I Disorders (Clinicians’ Version) or SCID-CV and the DN4 interview tool for neuropathic pain. The questionnaire also sourced demographic data from all participants. Age is summarised using non-parametric statistics. Categorical variables are summarised using percentages and a bar graph. The Chi-squared and the Fisher’s exact tests are used to compare binary categorical variables. The Prevalence Ratio is the relative measure of association used. The p-value is set at ≤0.05 for statistical significance. The 95% confidence interval (95 =% CI) depicts the precision of estimates. Ethical and access approval were granted by the University of Cape Town Research Ethics Committee and the Mpumalanga Department of Health respectively.
Results: Participants were recruited at kaMhlushwa clinic (n = 203 or 39.96%; 95% CI: 35.67 – 44.37), Naas clinic (n = 126 or 24.80%) and Mangweni clinic. There were more females (77.56%; 95% CI: 73.68 – 81.12; n = 394) than males (22.44%; 95% CI: 18.88 – 26.32; n = 114). Pain prevalence was 46.06%; 95% CI: 41.66 – 50.51 (n = 234). The prevalence of neuropathic pain was 17.72%; 95% CI: 14.49 – 21.32 (n = 90) and that of anxiety disorders among those participants with Neuropathic pain was 80%; 95% CI: 70.25 – 87.69 (n = 72).
Conclusion: This study confirmed the high prevalence of a complex disease burden in a high HIV prevalent Primary Care setting. The community has high prevalence of pain, anxiety disorders and neuropathic pain amongst PLWHIV patients on HAART. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/29483 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:28.941Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | Department of Public Health and Family Medicine |
| publisherStr | Department of Public Health and Family Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/29483 Prevalence of anxiety disorders among people living with HIV (PLWHIV) and experiencing neuropathic pain who attend clinics in Nkomazi Sub-District Ochan, Walter O Gwyther, Liz Palliative Medicine Background: Clinical and research experience indicates that a high HIV prevalence setting will have a high occurrence of conditions that are associated with HIV. These conditions are not always infectious in nature. General physiological pain, neuropathic pain (NeuP) and anxiety disorders are conditions that have a high prevalence in people living with HIV (PLWHIV). There is, however, a literature gap on the prevalence of these conditions in Nkomazi Sub-district in South Africa’s Mpumalanga Province. This study therefore aimed to serve as a baseline study for the determination of the prevalence of anxiety disorders and neuropathic pain amongst PLWHIV who attended Highly Active Antiretroviral Therapy (HAART) clinics in Nkomazi Sub-district. Aim of the study: To determine the prevalence of anxiety disorders among PLWHIV with neuropathic pain who attended HAART clinics in Nkomazi sub-district. Objectives of the study: 1) To determine the prevalence of Neuropathic Pain among patients attending HIV clinics in Nkomazi Health District; 2) To determine the prevalence of Anxiety disorders among PLWHIV experiencing neuropathic pain who attended HIV clinics in Nkomazi sub-district. 3) To determine the Types of Anxiety Disorder among Nkomazi PLWHIV with NeuP who have one, or more anxiety disorders. Methods: The objectives were achieved through a cross-sectional study using an interviewer administered questionnaire. Three out of 34 facilities were sampled for the study and participants were recruited and interviewed for a month in April 2013. A total of 508 participants were recruited. The questionnaire was adapted from the Structured Clinical Interview DSM IV Axis I Disorders (Clinicians’ Version) or SCID-CV and the DN4 interview tool for neuropathic pain. The questionnaire also sourced demographic data from all participants. Age is summarised using non-parametric statistics. Categorical variables are summarised using percentages and a bar graph. The Chi-squared and the Fisher’s exact tests are used to compare binary categorical variables. The Prevalence Ratio is the relative measure of association used. The p-value is set at ≤0.05 for statistical significance. The 95% confidence interval (95 =% CI) depicts the precision of estimates. Ethical and access approval were granted by the University of Cape Town Research Ethics Committee and the Mpumalanga Department of Health respectively. Results: Participants were recruited at kaMhlushwa clinic (n = 203 or 39.96%; 95% CI: 35.67 – 44.37), Naas clinic (n = 126 or 24.80%) and Mangweni clinic. There were more females (77.56%; 95% CI: 73.68 – 81.12; n = 394) than males (22.44%; 95% CI: 18.88 – 26.32; n = 114). Pain prevalence was 46.06%; 95% CI: 41.66 – 50.51 (n = 234). The prevalence of neuropathic pain was 17.72%; 95% CI: 14.49 – 21.32 (n = 90) and that of anxiety disorders among those participants with Neuropathic pain was 80%; 95% CI: 70.25 – 87.69 (n = 72). Conclusion: This study confirmed the high prevalence of a complex disease burden in a high HIV prevalent Primary Care setting. The community has high prevalence of pain, anxiety disorders and neuropathic pain amongst PLWHIV patients on HAART. 2019-02-11T13:35:24Z 2019-02-11T13:35:24Z 2018 2019-02-11T09:47:31Z Master Thesis Masters MPhil http://hdl.handle.net/11427/29483 eng application/pdf Department of Public Health and Family Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Palliative Medicine Ochan, Walter O Prevalence of anxiety disorders among people living with HIV (PLWHIV) and experiencing neuropathic pain who attend clinics in Nkomazi Sub-District |
| thesis_degree_str | Master's |
| title | Prevalence of anxiety disorders among people living with HIV (PLWHIV) and experiencing neuropathic pain who attend clinics in Nkomazi Sub-District |
| title_full | Prevalence of anxiety disorders among people living with HIV (PLWHIV) and experiencing neuropathic pain who attend clinics in Nkomazi Sub-District |
| title_fullStr | Prevalence of anxiety disorders among people living with HIV (PLWHIV) and experiencing neuropathic pain who attend clinics in Nkomazi Sub-District |
| title_full_unstemmed | Prevalence of anxiety disorders among people living with HIV (PLWHIV) and experiencing neuropathic pain who attend clinics in Nkomazi Sub-District |
| title_short | Prevalence of anxiety disorders among people living with HIV (PLWHIV) and experiencing neuropathic pain who attend clinics in Nkomazi Sub-District |
| title_sort | prevalence of anxiety disorders among people living with hiv plwhiv and experiencing neuropathic pain who attend clinics in nkomazi sub district |
| topic | Palliative Medicine |
| url | http://hdl.handle.net/11427/29483 |
| work_keys_str_mv | AT ochanwaltero prevalenceofanxietydisordersamongpeoplelivingwithhivplwhivandexperiencingneuropathicpainwhoattendclinicsinnkomazisubdistrict |