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The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism
Purpose: There are conflicting results from studies on whether the ventilation (V) scintigraphy can be safely omitted or replaced by a chest x-ray. These studies were based on planar ventilation perfusion (V/Q) scintigraphy. We evaluated the value of the V single photon emission computed tomography...
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| Format: | Thesis |
| Language: | English |
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Department of Radiation Medicine
2019
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| _version_ | 1867613203541786624 |
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| access_status_str | Open Access |
| author | Abubakar, Sofiullah |
| author2 | Kotze, Tessa |
| author_browse | Abubakar, Sofiullah Kotze, Tessa |
| author_facet | Kotze, Tessa Abubakar, Sofiullah |
| author_sort | Abubakar, Sofiullah |
| collection | Thesis |
| description | Purpose: There are conflicting results from studies on whether the ventilation (V) scintigraphy can be safely omitted or replaced by a chest x-ray. These studies were based on planar ventilation perfusion (V/Q) scintigraphy. We evaluated the value of the V single photon emission computed tomography (SPECT) on the final conclusion drawn from a V/Q SPECT and the possible role of the chest x-ray as a surrogate for the V SPECT. Methods Raw data of V/Q SPECT images and chest x-ray acquired within 48 hours over 18 months period were retrieved, reprocessed and reviewed in batches. The V SPECT, Q SPECT and chest x-ray were reviewed separately and in combination. Data on the presence and character of defects and chest x-ray abnormalities were recorded. The V/Q SPECT images were interpreted using the criteria in the EANM guideline and the Q SPECT and chest x-ray images were interpreted using the PISAPED criteria. Agreement between the diagnosis on the V/Q SPECT review and the Q SPECT and chest x-ray review was analysed. Results 21.1% of the patients were classified as 'PE present’ on the V/Q SPECT review whereas 48.9% were classified as 'PE present’ on the Q SPECT and chest x-ray review. Only 5.4% of defects seen on V SPECT had matched chest x-ray lung field opacity. Conclusion Our study showed that the omission of a V SPECT led to a high rate of false positive diagnoses and that the ventilation scan cannot be replaced by a chest x-ray. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/29578 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:24.523Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | Department of Radiation Medicine |
| publisherStr | Department of Radiation Medicine |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/29578 The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism Abubakar, Sofiullah Kotze, Tessa Mann, Mike D Nuclear Medicine Purpose: There are conflicting results from studies on whether the ventilation (V) scintigraphy can be safely omitted or replaced by a chest x-ray. These studies were based on planar ventilation perfusion (V/Q) scintigraphy. We evaluated the value of the V single photon emission computed tomography (SPECT) on the final conclusion drawn from a V/Q SPECT and the possible role of the chest x-ray as a surrogate for the V SPECT. Methods Raw data of V/Q SPECT images and chest x-ray acquired within 48 hours over 18 months period were retrieved, reprocessed and reviewed in batches. The V SPECT, Q SPECT and chest x-ray were reviewed separately and in combination. Data on the presence and character of defects and chest x-ray abnormalities were recorded. The V/Q SPECT images were interpreted using the criteria in the EANM guideline and the Q SPECT and chest x-ray images were interpreted using the PISAPED criteria. Agreement between the diagnosis on the V/Q SPECT review and the Q SPECT and chest x-ray review was analysed. Results 21.1% of the patients were classified as 'PE present’ on the V/Q SPECT review whereas 48.9% were classified as 'PE present’ on the Q SPECT and chest x-ray review. Only 5.4% of defects seen on V SPECT had matched chest x-ray lung field opacity. Conclusion Our study showed that the omission of a V SPECT led to a high rate of false positive diagnoses and that the ventilation scan cannot be replaced by a chest x-ray. 2019-02-18T10:01:07Z 2019-02-18T10:01:07Z 2018 2019-02-18T09:39:18Z Master Thesis Masters MMed http://hdl.handle.net/11427/29578 eng application/pdf Department of Radiation Medicine Faculty of Health Sciences University of Cape Town |
| spellingShingle | Nuclear Medicine Abubakar, Sofiullah The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism |
| thesis_degree_str | Master's |
| title | The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism |
| title_full | The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism |
| title_fullStr | The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism |
| title_full_unstemmed | The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism |
| title_short | The conclusions drawn from ventilation/perfusion single photon emission computed tomography (SPECT) compared to lung perfusion SPECT and a chest x-ray (CXR) in patients with suspected pulmonary pulmonary thromboembolism |
| title_sort | conclusions drawn from ventilation perfusion single photon emission computed tomography spect compared to lung perfusion spect and a chest x ray cxr in patients with suspected pulmonary pulmonary thromboembolism |
| topic | Nuclear Medicine |
| url | http://hdl.handle.net/11427/29578 |
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