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Investigation into synthetic protease-sensitive hydrogels as siRNA nanoparticle delivery vehicles.

RNA interference (RNAi) is receiving increasing attention as a form of gene regulation able to temporarily silence gene expression through post transcriptional mechanisms. RNAi agents have shown promise in targeting a range of ailments from cancers to myocardial infarction. However, RNAi based thera...

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Bibliographic Details
Main Author: Doubell, Emma
Other Authors: Davies, Neil H
Format: Thesis
Language:English
Published: Department of Surgery 2019
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