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Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey
Background High incidence of post-operative trichiasis and other poor outcomes after surgery in most trachoma-endemic settings poses a major challenge to global elimination of trachoma. This systematic review aimed to assess the incidence of post-operative trichiasis and other poor outcomes of tric...
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Division of General Surgery
2019
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| _version_ | 1867613343375687680 |
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| access_status_str | Open Access |
| author | Mwangi, Grace Wangari |
| author2 | Courtright, Paul |
| author_browse | Courtright, Paul Mwangi, Grace Wangari |
| author_facet | Courtright, Paul Mwangi, Grace Wangari |
| author_sort | Mwangi, Grace Wangari |
| collection | Thesis |
| description | Background
High incidence of post-operative trichiasis and other poor outcomes after surgery in most trachoma-endemic settings poses a major challenge to global elimination of trachoma. This systematic review aimed to assess the incidence of post-operative trichiasis and other poor outcomes of trichiasis surgery in Africa, based on findings of observational and interventional studies.
Search methods
We searched PubMed, Academic Search Premier, Africa-Wide Information, CINAHL and Health Source Nursing through EBSCOhost, Web of Science [all databases], and Cochrane Central Register of
Controlled Trials for relevant studies on the subject. We also searched the reference lists of included
studies to identify further potentially relevant studies. We included all observational and interventional studies that measured post-operative trichiasis as one of the primary outcomes. Only studies conducted in Africa were included in this review.
Data collection and analysis
Two reviewers independently screened the titles and abstracts, selected and assessed the articles for inclusion in this review. Any disagreements were resolved through discussion or by consulting a third reviewer. Where necessary, the corresponding authors of included studies were contacted to provide any missing data. Our primary outcome was post-operative trichiasis, which was defined as any eyelash touching the globe at different time points after surgery.
Main results
Thirty-five studies, including 12,943 participants, met the inclusion criteria. A number of the studies included in this review utilized the same data to measure the incidence of post-operative trichiasis and other poor outcomes over different follow-up periods.
Overall, a review of the included studies revealed a pattern of high incidence of post-operative trichiasis and other poor outcomes ranging from 2.3 at 6 weeks to 65% at 7 years. This incidence varied by type of study design, surgical procedure and technique used as well as the follow up period among other factors. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/30108 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:34:38.153Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2019 |
| publishDateRange | 2019 |
| publishDateSort | 2019 |
| publisher | Division of General Surgery |
| publisherStr | Division of General Surgery |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/30108 Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey Mwangi, Grace Wangari Courtright, Paul post-operative trichiasis, trachoma, trichiasis surgery Background High incidence of post-operative trichiasis and other poor outcomes after surgery in most trachoma-endemic settings poses a major challenge to global elimination of trachoma. This systematic review aimed to assess the incidence of post-operative trichiasis and other poor outcomes of trichiasis surgery in Africa, based on findings of observational and interventional studies. Search methods We searched PubMed, Academic Search Premier, Africa-Wide Information, CINAHL and Health Source Nursing through EBSCOhost, Web of Science [all databases], and Cochrane Central Register of Controlled Trials for relevant studies on the subject. We also searched the reference lists of included studies to identify further potentially relevant studies. We included all observational and interventional studies that measured post-operative trichiasis as one of the primary outcomes. Only studies conducted in Africa were included in this review. Data collection and analysis Two reviewers independently screened the titles and abstracts, selected and assessed the articles for inclusion in this review. Any disagreements were resolved through discussion or by consulting a third reviewer. Where necessary, the corresponding authors of included studies were contacted to provide any missing data. Our primary outcome was post-operative trichiasis, which was defined as any eyelash touching the globe at different time points after surgery. Main results Thirty-five studies, including 12,943 participants, met the inclusion criteria. A number of the studies included in this review utilized the same data to measure the incidence of post-operative trichiasis and other poor outcomes over different follow-up periods. Overall, a review of the included studies revealed a pattern of high incidence of post-operative trichiasis and other poor outcomes ranging from 2.3 at 6 weeks to 65% at 7 years. This incidence varied by type of study design, surgical procedure and technique used as well as the follow up period among other factors. 2019-05-15T09:57:33Z 2019-05-15T09:57:33Z 2019 2019-05-13T13:39:32Z Master Thesis Masters MPH http://hdl.handle.net/11427/30108 eng application/pdf Division of General Surgery Faculty of Health Sciences |
| spellingShingle | post-operative trichiasis, trachoma, trichiasis surgery Mwangi, Grace Wangari Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey |
| thesis_degree_str | Master's |
| title | Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey |
| title_full | Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey |
| title_fullStr | Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey |
| title_full_unstemmed | Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey |
| title_short | Post-operative Trachomatous Trichiasis in Africa: a systematic review and online survey |
| title_sort | post operative trachomatous trichiasis in africa a systematic review and online survey |
| topic | post-operative trichiasis, trachoma, trichiasis surgery |
| url | http://hdl.handle.net/11427/30108 |
| work_keys_str_mv | AT mwangigracewangari postoperativetrachomatoustrichiasisinafricaasystematicreviewandonlinesurvey |