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Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites
Includes abstract.
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Department of Molecular and Cell Biology
2014
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| _version_ | 1867613162067460096 |
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| access_status_str | Open Access |
| author | Ngandu, Nobubelo Kwanele |
| author2 | Seoighe, Cathal |
| author_browse | Ngandu, Nobubelo Kwanele Seoighe, Cathal |
| author_facet | Seoighe, Cathal Ngandu, Nobubelo Kwanele |
| author_sort | Ngandu, Nobubelo Kwanele |
| collection | Thesis |
| description | Includes abstract. |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3072 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:31:45.395Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Department of Molecular and Cell Biology |
| publisherStr | Department of Molecular and Cell Biology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3072 Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites Ngandu, Nobubelo Kwanele Seoighe, Cathal Cell Biology Includes abstract. Includes bibliographical references (p. 136-165). This thesis exposes previously ignored evolutionary characteristics of the synonymous sites of virus nucleotide sequences and contributes new findings to the understanding of the evolution of HIV-1 in relation to the human immune response. 2014-07-28T14:50:32Z 2014-07-28T14:50:32Z 2009 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3072 eng application/pdf Department of Molecular and Cell Biology Faculty of Science University of Cape Town |
| spellingShingle | Cell Biology Ngandu, Nobubelo Kwanele Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites |
| thesis_degree_str | Doctoral |
| title | Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites |
| title_full | Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites |
| title_fullStr | Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites |
| title_full_unstemmed | Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites |
| title_short | Evolutionary analyses of HIV-1 protein-coding sequences : adaptation to host cytotoxic immune responses and purifying selection at synonymous sites |
| title_sort | evolutionary analyses of hiv 1 protein coding sequences adaptation to host cytotoxic immune responses and purifying selection at synonymous sites |
| topic | Cell Biology |
| url | http://hdl.handle.net/11427/3072 |
| work_keys_str_mv | AT ngandunobubelokwanele evolutionaryanalysesofhiv1proteincodingsequencesadaptationtohostcytotoxicimmuneresponsesandpurifyingselectionatsynonymoussites |