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Gastric remnant carcinoma : histochemical and immunohistochemical profile
Includes bibliographical references (leaves 52-65).
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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Division of Anatomical Pathology
2014
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| _version_ | 1867613222071173120 |
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| access_status_str | Open Access |
| author | Elazzabi, Tawfik |
| author2 | Mall, Anwar S |
| author_browse | Elazzabi, Tawfik Mall, Anwar S |
| author_facet | Mall, Anwar S Elazzabi, Tawfik |
| author_sort | Elazzabi, Tawfik |
| collection | Thesis |
| description | Includes bibliographical references (leaves 52-65). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3076 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:32:42.829Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Anatomical Pathology |
| publisherStr | Division of Anatomical Pathology |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3076 Gastric remnant carcinoma : histochemical and immunohistochemical profile Elazzabi, Tawfik Mall, Anwar S Anatomical Pathology Includes bibliographical references (leaves 52-65). Gastric remnant carcinoma (GRC) is a gastric cancer that develops in gastric remnant more than five years after resection for benign disease. GRC comprises 1 %-9% of all gastric cancers. Partial gastrectomy for peptic ulcer is thought to be a risk factor for GRC. Pancreato-duodenal and bile reflux may play an important part in the aetiology of GRC. Primary gastric carcinoma (pGC) is a gastric cancer that arises in un-operated stomach and chronic gastritis is a well-known risk factor. Consequently there appear to be differences in the aetiology of GRC and PGC. According to many studies, surgical treatment of early GRC (Stage I or II) resulted in the same or better prognosis with similar stage PGC. However if diagnosed late, GRC has a worse prognosis than PGC at the same stage. In this study haematoxylin and eosin, alcian blue pH 2.5, periodic acid Schiff, high iron diamine and Giemsa stains as well as immunohistochemical methods (eight antibodies against MUCI to MUC6) were used to determine the type of mucin and the pattern of staining in twenty cases of GRC and twenty PGC (ten cases of intestinal type PGC, ten diffuse type PGC) and ten normal gastric mucosal biopsies. The aim of the study was to describe the morphology of GRC and the adjacent gastric mucosa, as well as to determine the histochemical and immunohistochemical mucin profile of GRC and to compare this with that of PGC and normal mucosa. 2014-07-28T14:51:31Z 2014-07-28T14:51:31Z 2004 Master Thesis Masters MMed http://hdl.handle.net/11427/3076 eng application/pdf Division of Anatomical Pathology Faculty of Health Sciences University of Cape Town |
| spellingShingle | Anatomical Pathology Elazzabi, Tawfik Gastric remnant carcinoma : histochemical and immunohistochemical profile |
| thesis_degree_str | Master's |
| title | Gastric remnant carcinoma : histochemical and immunohistochemical profile |
| title_full | Gastric remnant carcinoma : histochemical and immunohistochemical profile |
| title_fullStr | Gastric remnant carcinoma : histochemical and immunohistochemical profile |
| title_full_unstemmed | Gastric remnant carcinoma : histochemical and immunohistochemical profile |
| title_short | Gastric remnant carcinoma : histochemical and immunohistochemical profile |
| title_sort | gastric remnant carcinoma histochemical and immunohistochemical profile |
| topic | Anatomical Pathology |
| url | http://hdl.handle.net/11427/3076 |
| work_keys_str_mv | AT elazzabitawfik gastricremnantcarcinomahistochemicalandimmunohistochemicalprofile |