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Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5
Includes bibliographical references (p. 100-119).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Medical Biochemistry
2014
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| _version_ | 1867614496323796992 |
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| access_status_str | Open Access |
| author | Folefoc, Asongna Theresia Forkem |
| author2 | Flanagan, Colleen |
| author_browse | Flanagan, Colleen Folefoc, Asongna Theresia Forkem |
| author_facet | Flanagan, Colleen Folefoc, Asongna Theresia Forkem |
| author_sort | Folefoc, Asongna Theresia Forkem |
| collection | Thesis |
| description | Includes bibliographical references (p. 100-119). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3128 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:52:58.092Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Medical Biochemistry |
| publisherStr | Division of Medical Biochemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3128 Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 Folefoc, Asongna Theresia Forkem Flanagan, Colleen Katz, Arieh Medical Biochemistry Includes bibliographical references (p. 100-119). Four mutations of the CCR5 receptor have been identified in the South African population, but the effects of these mutations on CCR5 function and HIV infection are unknown. We have used in vitro methods to assess the ffect of the mutations, Asp2Val, Leu107Phe, Arg225Gln and Arg225stop, on CCR5 interactions with chemokine ligands and HIV. 2014-07-28T14:54:55Z 2014-07-28T14:54:55Z 2007 Doctoral Thesis Doctoral PhD http://hdl.handle.net/11427/3128 eng application/pdf Division of Medical Biochemistry Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medical Biochemistry Folefoc, Asongna Theresia Forkem Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 |
| thesis_degree_str | Doctoral |
| title | Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 |
| title_full | Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 |
| title_fullStr | Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 |
| title_full_unstemmed | Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 |
| title_short | Functional consequences of South African mutations of the HIV-1 co-receptor, CCR5 |
| title_sort | functional consequences of south african mutations of the hiv 1 co receptor ccr5 |
| topic | Medical Biochemistry |
| url | http://hdl.handle.net/11427/3128 |
| work_keys_str_mv | AT folefocasongnatheresiaforkem functionalconsequencesofsouthafricanmutationsofthehiv1coreceptorccr5 |