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A Molecular Basis for the C-Domain Selectivity of Angiotensin-Converting Enzyme

Angiotensin-Converting Enzyme (ACE) plays an essential role in blood pressure regulationand ACE inhibitors are widely used to treat cardiovascular disease. Two isoforms exist,somatic ACE (sACE) consisting of two homologous domains, N- and C-domain, and testisACE (tACE), corresponding to the C-domain...

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Bibliographic Details
Main Author: Kroger, W
Other Authors: Sturrock, Edward D
Format: Thesis
Language:English
Published: Division of Medical Biochemistry 2014
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