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The role of the CCR5 co-receptor conformation in HIV fusion
Includes bibliographical references (leaves 71-80).
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| Main Author: | |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
Division of Medical Biochemistry
2014
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| _version_ | 1867613760001146880 |
|---|---|
| access_status_str | Open Access |
| author | Salo, Alex |
| author2 | Flanagan, Colleen |
| author_browse | Flanagan, Colleen Salo, Alex |
| author_facet | Flanagan, Colleen Salo, Alex |
| author_sort | Salo, Alex |
| collection | Thesis |
| description | Includes bibliographical references (leaves 71-80). |
| format | Thesis |
| id | oai:open.uct.ac.za:11427/3150 |
| institution | University of Cape Town (South Africa) |
| language | eng |
| last_indexed | 2026-06-10T12:41:15.880Z |
| license_str | Not specified — see source repository |
| provenance_str_mv | Harvested via OAI-PMH from UCTD — University of Cape Town Open Access Repository |
| publishDate | 2014 |
| publishDateRange | 2014 |
| publishDateSort | 2014 |
| publisher | Division of Medical Biochemistry |
| publisherStr | Division of Medical Biochemistry |
| record_format | dspace |
| source_str | UCTD — University of Cape Town Open Access Repository |
| spelling | oai:open.uct.ac.za:11427/3150 The role of the CCR5 co-receptor conformation in HIV fusion Salo, Alex Flanagan, Colleen Medical Biochemistry Includes bibliographical references (leaves 71-80). This thesis aimed to better define the co-receptor conformation by determining whether mutants of the CCR5 receptor stabilized in the active conformation were less able to mediate HIV fussion. Eight mutant receptors were generated by site-directed mutagenesis and screened for constitutive activity using intracellutal signaling assays. 2014-07-28T14:55:59Z 2014-07-28T14:55:59Z 2008 Master Thesis Masters MSc http://hdl.handle.net/11427/3150 eng application/pdf Division of Medical Biochemistry Faculty of Health Sciences University of Cape Town |
| spellingShingle | Medical Biochemistry Salo, Alex The role of the CCR5 co-receptor conformation in HIV fusion |
| thesis_degree_str | Master's |
| title | The role of the CCR5 co-receptor conformation in HIV fusion |
| title_full | The role of the CCR5 co-receptor conformation in HIV fusion |
| title_fullStr | The role of the CCR5 co-receptor conformation in HIV fusion |
| title_full_unstemmed | The role of the CCR5 co-receptor conformation in HIV fusion |
| title_short | The role of the CCR5 co-receptor conformation in HIV fusion |
| title_sort | role of the ccr5 co receptor conformation in hiv fusion |
| topic | Medical Biochemistry |
| url | http://hdl.handle.net/11427/3150 |
| work_keys_str_mv | AT saloalex theroleoftheccr5coreceptorconformationinhivfusion AT saloalex roleoftheccr5coreceptorconformationinhivfusion |